Role of YB-1 in Regulation of Poly(ADP-Ribosylation) Catalyzed by Poly(ADP-Ribose) Polymerases

Poly(ADP-ribosyl)ation is a post-translational modification of proteins that performs an essential regulatory function in the cellular response to DNA damage. The key enzyme synthesizing poly(ADP-ribose) (PAR) in the cells is poly(ADP-ribose) polymerase 1 (PARP1). Understanding the mechanisms of the...

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Veröffentlicht in:	Biochemistry (Moscow) 2022, Vol.87 (Suppl 1), p.S32-S47
Hauptverfasser:	Alemasova, Elizaveta E., Naumenko, Konstantin N., Sukhanova, Maria V., Lavrik, Olga I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine diphosphate ADP-ribosylation Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Catalysis DNA Damage DNA repair Enzymes Genomes Life Sciences Metabolism Microbiology Nuclear factor I Poly Adenosine Diphosphate Ribose Poly ADP Ribosylation Poly(ADP-ribose) Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerases - metabolism Post-translation Proteins Proteins - metabolism Regulation Review Ribonucleic acid Ribose Ribosylation RNA RNA-binding protein
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