Voluntary wheel running exercise regulates microglia polarization in hippocampus through STAT3 signal pathway to inhibit depression-like behavior induced by chronic stress in rats

This paper was aimed to investigate the effect of voluntary wheel running exercise on depression-like behavior induced by chronic water immersion restraint stress (CWIRS) and the underlying mechanism. Sprague-Dawley (SD) rats received CWIRS to induce depression-like behavior and 4-week voluntary whe...

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Veröffentlicht in:	Sheng li hsüeh pao 2022-04, Vol.74 (2), p.177-187
Hauptverfasser:	Luo, Jie, Wang, Jing-Qiong, Xie, Li-Na, Meng, An-Na, Zheng, Si-Si, Zhou, Shou-Hong
Format:	Artikel
Sprache:	chi
Schlagworte:	Animals Depression - etiology Hippocampus - metabolism Lipopolysaccharides - metabolism Microglia - metabolism Motor Activity Rats Rats, Sprague-Dawley Signal Transduction
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