Reducing Staphylococcus aureus infections in the neonatal intensive care unit
Objective Our neonatal intensive care unit (NICU) saw an increase in Staphylococcus aureus (SA) infections—methicillin-resistant SA (MRSA) infections increased from 2.1/10,000 patient days (PD) to 5.1/10,000 PD, and methicillin-sensitive SA (MSSA) infections from 1.2/10,000 PD to 3.9/10,000 PD. This...
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| Veröffentlicht in: | Journal of perinatology 2022-11, Vol.42 (11), p.1540-1545 |
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| container_title | Journal of perinatology |
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| creator | Nickel, Noura Brooks, Sandra Mize, Chris Messina, Allison |
| description | Objective
Our neonatal intensive care unit (NICU) saw an increase in
Staphylococcus aureus
(SA) infections—methicillin-resistant SA (MRSA) infections increased from 2.1/10,000 patient days (PD) to 5.1/10,000 PD, and methicillin-sensitive SA (MSSA) infections from 1.2/10,000 PD to 3.9/10,000 PD. This quality improvement project aimed to decrease the rates of SA infections to less than 2.0/10,000 PD, and to determine the rate of SA decolonization.
Methods
Infection prevention interventions targeted patient factors (SA surveillance, patient cohorting, decolonization protocol), provider factors (provider cohorting, enhanced hand hygiene) and environmental factors (room structure, equipment optimization).
Results
The rates of MRSA and MSSA infections decreased to 0.6/10,000 PD and 0.7 infections/10,000 PD respectively. Persistent decolonization of SA was successful in 67% of colonized patients.
Conclusions
Specific interventions targeting patient, provider, and environmental factors, including the implementation of a SA decolonization protocol, were successful in decreasing the incidence of SA infections in neonates. |
| doi_str_mv | 10.1038/s41372-022-01407-4 |
| format | Article |
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Our neonatal intensive care unit (NICU) saw an increase in
Staphylococcus aureus
(SA) infections—methicillin-resistant SA (MRSA) infections increased from 2.1/10,000 patient days (PD) to 5.1/10,000 PD, and methicillin-sensitive SA (MSSA) infections from 1.2/10,000 PD to 3.9/10,000 PD. This quality improvement project aimed to decrease the rates of SA infections to less than 2.0/10,000 PD, and to determine the rate of SA decolonization.
Methods
Infection prevention interventions targeted patient factors (SA surveillance, patient cohorting, decolonization protocol), provider factors (provider cohorting, enhanced hand hygiene) and environmental factors (room structure, equipment optimization).
Results
The rates of MRSA and MSSA infections decreased to 0.6/10,000 PD and 0.7 infections/10,000 PD respectively. Persistent decolonization of SA was successful in 67% of colonized patients.
Conclusions
Specific interventions targeting patient, provider, and environmental factors, including the implementation of a SA decolonization protocol, were successful in decreasing the incidence of SA infections in neonates.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-022-01407-4</identifier><identifier>PMID: 35487977</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/699/255/1318 ; 692/700/459/1748 ; Algorithms ; Cross Infection - epidemiology ; Cross Infection - prevention & control ; Decolonization ; Drug resistance ; Environmental factors ; Gestational age ; Hospitals ; Humans ; Hygiene ; Infant, Newborn ; Infections ; Intensive care ; Intensive Care Units, Neonatal ; Intervention ; Medicine ; Medicine & Public Health ; Methicillin ; Methicillin-Resistant Staphylococcus aureus ; Neonatal care ; Neonates ; Newborn babies ; Optimization ; Patients ; Pediatric Surgery ; Pediatrics ; Personal hygiene ; Personal protective equipment ; Prevention ; Quality control ; Quality improvement ; Quality Improvement Article ; Retrospective Studies ; Staphylococcal Infections - epidemiology ; Staphylococcal Infections - prevention & control ; Staphylococcus aureus ; Staphylococcus infections</subject><ispartof>Journal of perinatology, 2022-11, Vol.42 (11), p.1540-1545</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer Nature America, Inc.</rights><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c305t-ce82a43d540fe42cfc60460987c0e5c4adb370eacc74cbb5c8b4a19a8d6d5c913</citedby><cites>FETCH-LOGICAL-c305t-ce82a43d540fe42cfc60460987c0e5c4adb370eacc74cbb5c8b4a19a8d6d5c913</cites><orcidid>0000-0003-4952-7869</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41372-022-01407-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/s41372-022-01407-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35487977$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nickel, Noura</creatorcontrib><creatorcontrib>Brooks, Sandra</creatorcontrib><creatorcontrib>Mize, Chris</creatorcontrib><creatorcontrib>Messina, Allison</creatorcontrib><title>Reducing Staphylococcus aureus infections in the neonatal intensive care unit</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><addtitle>J Perinatol</addtitle><description>Objective
Our neonatal intensive care unit (NICU) saw an increase in
Staphylococcus aureus
(SA) infections—methicillin-resistant SA (MRSA) infections increased from 2.1/10,000 patient days (PD) to 5.1/10,000 PD, and methicillin-sensitive SA (MSSA) infections from 1.2/10,000 PD to 3.9/10,000 PD. This quality improvement project aimed to decrease the rates of SA infections to less than 2.0/10,000 PD, and to determine the rate of SA decolonization.
Methods
Infection prevention interventions targeted patient factors (SA surveillance, patient cohorting, decolonization protocol), provider factors (provider cohorting, enhanced hand hygiene) and environmental factors (room structure, equipment optimization).
Results
The rates of MRSA and MSSA infections decreased to 0.6/10,000 PD and 0.7 infections/10,000 PD respectively. Persistent decolonization of SA was successful in 67% of colonized patients.
Conclusions
Specific interventions targeting patient, provider, and environmental factors, including the implementation of a SA decolonization protocol, were successful in decreasing the incidence of SA infections in neonates.</description><subject>692/699/255/1318</subject><subject>692/700/459/1748</subject><subject>Algorithms</subject><subject>Cross Infection - epidemiology</subject><subject>Cross Infection - prevention & control</subject><subject>Decolonization</subject><subject>Drug resistance</subject><subject>Environmental factors</subject><subject>Gestational age</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hygiene</subject><subject>Infant, Newborn</subject><subject>Infections</subject><subject>Intensive care</subject><subject>Intensive Care Units, Neonatal</subject><subject>Intervention</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Methicillin</subject><subject>Methicillin-Resistant Staphylococcus aureus</subject><subject>Neonatal care</subject><subject>Neonates</subject><subject>Newborn babies</subject><subject>Optimization</subject><subject>Patients</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Personal hygiene</subject><subject>Personal protective equipment</subject><subject>Prevention</subject><subject>Quality control</subject><subject>Quality improvement</subject><subject>Quality Improvement Article</subject><subject>Retrospective Studies</subject><subject>Staphylococcal Infections - epidemiology</subject><subject>Staphylococcal Infections - prevention & control</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus infections</subject><issn>0743-8346</issn><issn>1476-5543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kEtLxDAQx4Mouq5-AQ9S8OKlmmeTHkV8wYrg4xzS6XStdNM1aQW_vVnXB3jwECZhfvnP8CPkgNETRoU5jZIJzXPK02GS6lxukAmTusiVkmKTTKiWIjdCFjtkN8YXSldNvU12hJJGl1pPyO091iO0fp49DG75_N710AOMMXNjwFRa3yAMbe9X12x4xsxj793guvQe0Mf2DTNwAbPRt8Me2WpcF3H_q07J0-XF4_l1Pru7ujk_m-UgqBpyQMOdFLWStEHJoYGCyoKWRgNFBdLVldAUHYCWUFUKTCUdK52pi1pBycSUHK9zl6F_HTEOdtFGwK5zabsxWl4owwXTpUzo0R_0pR-DT9tZrnmphWG0SBRfUxD6GAM2dhnahQvvllG7km3Xsm2SbT9l21X04Vf0WC2w_vnybTcBYg3E1PJzDL-z_4n9AA9Birs</recordid><startdate>20221101</startdate><enddate>20221101</enddate><creator>Nickel, Noura</creator><creator>Brooks, Sandra</creator><creator>Mize, Chris</creator><creator>Messina, Allison</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7RV</scope><scope>7T5</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4952-7869</orcidid></search><sort><creationdate>20221101</creationdate><title>Reducing Staphylococcus aureus infections in the neonatal intensive care unit</title><author>Nickel, Noura ; Brooks, Sandra ; Mize, Chris ; Messina, Allison</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c305t-ce82a43d540fe42cfc60460987c0e5c4adb370eacc74cbb5c8b4a19a8d6d5c913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>692/699/255/1318</topic><topic>692/700/459/1748</topic><topic>Algorithms</topic><topic>Cross Infection - 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epidemiology</topic><topic>Staphylococcal Infections - prevention & control</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nickel, Noura</creatorcontrib><creatorcontrib>Brooks, Sandra</creatorcontrib><creatorcontrib>Mize, Chris</creatorcontrib><creatorcontrib>Messina, Allison</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nickel, Noura</au><au>Brooks, Sandra</au><au>Mize, Chris</au><au>Messina, Allison</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reducing Staphylococcus aureus infections in the neonatal intensive care unit</atitle><jtitle>Journal of perinatology</jtitle><stitle>J Perinatol</stitle><addtitle>J Perinatol</addtitle><date>2022-11-01</date><risdate>2022</risdate><volume>42</volume><issue>11</issue><spage>1540</spage><epage>1545</epage><pages>1540-1545</pages><issn>0743-8346</issn><eissn>1476-5543</eissn><abstract>Objective
Our neonatal intensive care unit (NICU) saw an increase in
Staphylococcus aureus
(SA) infections—methicillin-resistant SA (MRSA) infections increased from 2.1/10,000 patient days (PD) to 5.1/10,000 PD, and methicillin-sensitive SA (MSSA) infections from 1.2/10,000 PD to 3.9/10,000 PD. This quality improvement project aimed to decrease the rates of SA infections to less than 2.0/10,000 PD, and to determine the rate of SA decolonization.
Methods
Infection prevention interventions targeted patient factors (SA surveillance, patient cohorting, decolonization protocol), provider factors (provider cohorting, enhanced hand hygiene) and environmental factors (room structure, equipment optimization).
Results
The rates of MRSA and MSSA infections decreased to 0.6/10,000 PD and 0.7 infections/10,000 PD respectively. Persistent decolonization of SA was successful in 67% of colonized patients.
Conclusions
Specific interventions targeting patient, provider, and environmental factors, including the implementation of a SA decolonization protocol, were successful in decreasing the incidence of SA infections in neonates.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>35487977</pmid><doi>10.1038/s41372-022-01407-4</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-4952-7869</orcidid></addata></record> |
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| ispartof | Journal of perinatology, 2022-11, Vol.42 (11), p.1540-1545 |
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| source | MEDLINE; SpringerLink Journals |
| subjects | 692/699/255/1318 692/700/459/1748 Algorithms Cross Infection - epidemiology Cross Infection - prevention & control Decolonization Drug resistance Environmental factors Gestational age Hospitals Humans Hygiene Infant, Newborn Infections Intensive care Intensive Care Units, Neonatal Intervention Medicine Medicine & Public Health Methicillin Methicillin-Resistant Staphylococcus aureus Neonatal care Neonates Newborn babies Optimization Patients Pediatric Surgery Pediatrics Personal hygiene Personal protective equipment Prevention Quality control Quality improvement Quality Improvement Article Retrospective Studies Staphylococcal Infections - epidemiology Staphylococcal Infections - prevention & control Staphylococcus aureus Staphylococcus infections |
| title | Reducing Staphylococcus aureus infections in the neonatal intensive care unit |
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