New Aβ(1–42) ligands from anti-amyloid antibodies: Design, synthesis, and structural interaction

Alzheimer's disease (AD), is the most common neurodegenerative disorder of the aging population resulting in progressive cognitive and functional decline. Accumulation of amyloid plaques around neuronal cells is considered a critical pathogenetic event and, in most cases, a hallmark of the path...

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Veröffentlicht in:	European journal of medicinal chemistry 2022-07, Vol.237, p.114400-114400, Article 114400
Hauptverfasser:	Santoro, Angelo, Grimaldi, Manuela, Buonocore, Michela, Stillitano, Ilaria, Gloria, Antonio, Santin, Matteo, Bobba, Fabrizio, Sublimi Saponetti, Matilde, Ciaglia, Elena, D'Ursi, Anna Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Amyloid plaques Antibody Aptamers Biomarkers Immunotherapy Peptide design
Online-Zugang:	Volltext
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