Clinical relevance of increased antibody titres in older adults upon vaccination with squalene-adjuvanted versus non-adjuvanted influenza vaccines

In older adults, the serum antibody response to inactivated influenza vaccine (IIV) is often lower than in adolescents and non-elderly adults which may translate into suboptimal protection against influenza. To counteract this expression of immunosenescence, the use of adjuvanted IIV formulations ha...

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Veröffentlicht in:	Vaccine 2022-05, Vol.40 (23), p.3098-3102
Hauptverfasser:	Beyer, Walter E.P., Palache, Abraham M., Boulfich, Mimoun, Osterhaus, Albert D.M.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant Adjuvants Adolescents Adults Antibodies Antibody response Clinical relevance Clinical trials Immunization Immunogenicity Immunosenescence Influenza Influenza vaccine Older people Pandemics Severe acute respiratory syndrome coronavirus 2 Squalene Vaccines
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