Lower cerebral arterial blood flow is associated with greater serum neurofilament light chain levels in multiple sclerosis patients

Background and purpose Hypoperfusion, vascular pathology, and cardiovascular risk factors are associated with disease severity in multiple sclerosis (MS). We aimed to assess relationships between cerebral arterial blood flow (CABF) and serum neurofilament light chain (sNfL) as neuronal damage biomar...

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Veröffentlicht in:	European journal of neurology 2022-08, Vol.29 (8), p.2299-2308
Hauptverfasser:	Jakimovski, Dejan, Gibney, Brianna L., Marr, Karen, Ramasamy, Deepa P., Dwyer, Michael G., Bergsland, Niels, Weinstock‐Guttman, Bianca, Ramanathan, Murali, Zivadinov, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Blood flow Body mass Body mass index Body size Cardiovascular diseases cerebral arterial blood flow Chains Demographic variables Doppler effect Health risks Lesions Light levels Magnetic resonance imaging Multiple sclerosis Neuroimaging Pathology perfusion Regression analysis Regression models relapsing‐remitting multiple sclerosis Risk analysis Risk factors serum neurofilament light chain Statistical analysis
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