Combined multi-omics and network pharmacology approach reveals the role of Tripterygium Wilfordii Hook F in treating HIV immunological non-responders

The HIV-1 infected immunological non-responders (INRs) are characterized by poor immune reconstitution after long-term treatment. Tripterygium Wilfordii Hook F (TwHF) pill is a traditional Chinese patent drug with extensive immunosuppressive effects and has been clinically proven efficacy in treatin...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2022-07, Vol.101, p.154103-154103, Article 154103
Hauptverfasser:	Liu, Xiaosheng, Lin, Ling, Lv, Tingxia, Lu, Lianfeng, Li, Xiaodi, Han, Yang, Qiu, Zhifeng, Li, Xiaoxia, Li, Yanling, Song, Xiaojing, Cao, Wei, Li, Taisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	CD4 recovery Drugs, Chinese Herbal - chemistry HIV Infections - drug therapy Humans Immunological non-responder Interferon Leukocytes, Mononuclear Network Pharmacology Proteomics STAT1 Tripterygium - chemistry Tripterygium Wilfordii Hook F Triptolide
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