Enantioselective high‐performance liquid chromatography of aryl‐substituted oxazolines as an efficient tool for determination of chiral purity of serine medicinal components

A new approach for the evaluation of chiral purity of serine esterification products bearing long‐chain alkyl substituents was developed. The compounds were simply converted to aryl‐substituted oxazolines which: (i) facilitates effective chromatographic enantioseparation and (ii) enables direct dete...

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Veröffentlicht in:	Journal of separation science 2022-07, Vol.45 (13), p.2217-2227
Hauptverfasser:	Pomeisl, Karel, Vaňkátová, Petra, Hamplová, Věra
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds chiral purity Chirality Chromophores Enantiomers enantioselective chromatography enantioseparation Esterification Liquid chromatography oxazoline Polysaccharides Purity Rigid structures Substitutes Ultraviolet absorption
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