Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma

Phenolic acids represent a large collection of phytochemical molecules present in the plant kingdom; they have an important role as epigenetic regulators, particularly as inhibitors of DNA methylation. In the present study, 14 methyl benzoate and cinnamate analogs were synthesized (11–24). Their cyt...

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Veröffentlicht in:	Chemical biology & drug design 2022-08, Vol.100 (2), p.245-255
Hauptverfasser:	Castro‐Vazquez, Diana, Sánchez‐Carranza, Jessica Nayelli, Alvarez, Laura, Juárez‐Mercado, Karina Eurídice, Sánchez‐Cruz, Noberto, Medina‐Franco, José L., Antunez‐Mojica, Mayra, González‐Maya, Leticia
Format:	Artikel
Sprache:	eng
Schlagworte:	cancer cytotoxicity DNA methylation DNMT1 docking epigenetics natural products phenolic acids
Online-Zugang:	Volltext
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