Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis
Transfusion in acute aortic syndromes has been studied in a limited fashion. We sought to describe contemporary transfusion practice for root replacement in acute (Stanford) type A aortic dissection. The Society of Thoracic Surgeons Adult Cardiac Surgery Database was interrogated to identify patient...
Gespeichert in:
| Veröffentlicht in: | The Annals of thoracic surgery 2022-12, Vol.114 (6), p.2149-2156 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2156 |
|---|---|
| container_issue | 6 |
| container_start_page | 2149 |
| container_title | The Annals of thoracic surgery |
| container_volume | 114 |
| creator | Hemli, Jonathan M. Ducca, Emma L. Chaplin, William F. Arader, Lindsay L. Scheinerman, S. Jacob Lesser, Martin L. Ahn, Seungjun Mihelis, Efstathia A. Jahn, Lynda A. Patel, Nirav C. Brinster, Derek R. |
| description | Transfusion in acute aortic syndromes has been studied in a limited fashion. We sought to describe contemporary transfusion practice for root replacement in acute (Stanford) type A aortic dissection.
The Society of Thoracic Surgeons Adult Cardiac Surgery Database was interrogated to identify patients who underwent primary aortic root replacement for acute (Stanford) type A aortic dissection (July 2014 to June 2017). Patients (n = 1558) were stratified by type of root replacement. Multivariate regression was used to determine those variables associated with transfusion and postoperative morbidity.
Transfusion was required in 90.5% of cases (n = 1410). Operative mortality for all patients was 17.3% (261 deaths). Intraoperative red blood cell transfusion portended reduced short-term survival (odds ratio [OR] 2.00, P = .025). Massive postoperative transfusion was associated with prolonged ventilation (OR 13.47, P < .001), sepsis (OR 4.13, P |
| doi_str_mv | 10.1016/j.athoracsur.2022.03.068 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2654293531</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0003497522005197</els_id><sourcerecordid>2654293531</sourcerecordid><originalsourceid>FETCH-LOGICAL-c374t-bcb66eb8466501caf84a2dfab180f57dd20737a9a56e438bb85239ccebf2086e3</originalsourceid><addsrcrecordid>eNqFkE1v2zAMhoVhxZq1_QuDjrvYkyVLtnfL0n0BBQY06VmgZGpV4FiZJBfIv5-KdNtxJ4Lg85LgQwhtWN2wRn3Y15AfQwSbllhzxnnNRM1U_4qsGil5pbgcXpMVY0xU7dDJS_I2pX1peRm_IZdCtpIr1a6I20WYk1uSDzP1M70PIdN7PE5g8YBzpi5Eug4xe0tvfUpocyE_0t0j0u1uS9fjMmW6gTh6sHS7xJ8YT_QWMhhISNczTKfk0zW5cDAlvHmpV-Thy-fd5lt19-Pr9836rrKia3NlrFEKTd8qJVljwfUt8NGBaXrmZDeOnHWigwGkwlb0xvSSi8FaNI6zXqG4Iu_Pe48x_FowZX3wyeI0wYxhSZor2fJBSNEUtD-jNoaUIjp9jP4A8aQbpp8t673-Z1k_W9ZM6GK5RN-9XFnMAce_wT9aC_DpDGD59clj1Ml6nC2OPhaDegz-_1d-A4pLlE0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2654293531</pqid></control><display><type>article</type><title>Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Hemli, Jonathan M. ; Ducca, Emma L. ; Chaplin, William F. ; Arader, Lindsay L. ; Scheinerman, S. Jacob ; Lesser, Martin L. ; Ahn, Seungjun ; Mihelis, Efstathia A. ; Jahn, Lynda A. ; Patel, Nirav C. ; Brinster, Derek R.</creator><creatorcontrib>Hemli, Jonathan M. ; Ducca, Emma L. ; Chaplin, William F. ; Arader, Lindsay L. ; Scheinerman, S. Jacob ; Lesser, Martin L. ; Ahn, Seungjun ; Mihelis, Efstathia A. ; Jahn, Lynda A. ; Patel, Nirav C. ; Brinster, Derek R.</creatorcontrib><description>Transfusion in acute aortic syndromes has been studied in a limited fashion. We sought to describe contemporary transfusion practice for root replacement in acute (Stanford) type A aortic dissection.
The Society of Thoracic Surgeons Adult Cardiac Surgery Database was interrogated to identify patients who underwent primary aortic root replacement for acute (Stanford) type A aortic dissection (July 2014 to June 2017). Patients (n = 1558) were stratified by type of root replacement. Multivariate regression was used to determine those variables associated with transfusion and postoperative morbidity.
Transfusion was required in 90.5% of cases (n = 1410). Operative mortality for all patients was 17.3% (261 deaths). Intraoperative red blood cell transfusion portended reduced short-term survival (odds ratio [OR] 2.00, P = .025). Massive postoperative transfusion was associated with prolonged ventilation (OR 13.47, P < .001), sepsis (OR 4.13, P < .001), and new dialysis-dependent renal failure (OR 2.43, P < .001). Women were more likely to require transfusion (OR 3.03, P < .001), as were patients who had coronary artery bypass (OR 1.57, P = .009), and those in shock (OR 2.27, P < .001). Valve-sparing aortic root replacement was associated with reduced transfusion requirements vs composite roots. Institutional case volume was not appreciably correlated with transfusion.
Most patients undergoing root replacement for aortic dissection require blood products. Composite root replacement is associated with a greater likelihood of transfusion than a valve-sparing operation. Transfusion independently foreshadows greater operative mortality.
[Display omitted]</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2022.03.068</identifier><identifier>PMID: 35452664</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><ispartof>The Annals of thoracic surgery, 2022-12, Vol.114 (6), p.2149-2156</ispartof><rights>2022 The Society of Thoracic Surgeons</rights><rights>Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-bcb66eb8466501caf84a2dfab180f57dd20737a9a56e438bb85239ccebf2086e3</citedby><cites>FETCH-LOGICAL-c374t-bcb66eb8466501caf84a2dfab180f57dd20737a9a56e438bb85239ccebf2086e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35452664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hemli, Jonathan M.</creatorcontrib><creatorcontrib>Ducca, Emma L.</creatorcontrib><creatorcontrib>Chaplin, William F.</creatorcontrib><creatorcontrib>Arader, Lindsay L.</creatorcontrib><creatorcontrib>Scheinerman, S. Jacob</creatorcontrib><creatorcontrib>Lesser, Martin L.</creatorcontrib><creatorcontrib>Ahn, Seungjun</creatorcontrib><creatorcontrib>Mihelis, Efstathia A.</creatorcontrib><creatorcontrib>Jahn, Lynda A.</creatorcontrib><creatorcontrib>Patel, Nirav C.</creatorcontrib><creatorcontrib>Brinster, Derek R.</creatorcontrib><title>Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Transfusion in acute aortic syndromes has been studied in a limited fashion. We sought to describe contemporary transfusion practice for root replacement in acute (Stanford) type A aortic dissection.
The Society of Thoracic Surgeons Adult Cardiac Surgery Database was interrogated to identify patients who underwent primary aortic root replacement for acute (Stanford) type A aortic dissection (July 2014 to June 2017). Patients (n = 1558) were stratified by type of root replacement. Multivariate regression was used to determine those variables associated with transfusion and postoperative morbidity.
Transfusion was required in 90.5% of cases (n = 1410). Operative mortality for all patients was 17.3% (261 deaths). Intraoperative red blood cell transfusion portended reduced short-term survival (odds ratio [OR] 2.00, P = .025). Massive postoperative transfusion was associated with prolonged ventilation (OR 13.47, P < .001), sepsis (OR 4.13, P < .001), and new dialysis-dependent renal failure (OR 2.43, P < .001). Women were more likely to require transfusion (OR 3.03, P < .001), as were patients who had coronary artery bypass (OR 1.57, P = .009), and those in shock (OR 2.27, P < .001). Valve-sparing aortic root replacement was associated with reduced transfusion requirements vs composite roots. Institutional case volume was not appreciably correlated with transfusion.
Most patients undergoing root replacement for aortic dissection require blood products. Composite root replacement is associated with a greater likelihood of transfusion than a valve-sparing operation. Transfusion independently foreshadows greater operative mortality.
[Display omitted]</description><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqFkE1v2zAMhoVhxZq1_QuDjrvYkyVLtnfL0n0BBQY06VmgZGpV4FiZJBfIv5-KdNtxJ4Lg85LgQwhtWN2wRn3Y15AfQwSbllhzxnnNRM1U_4qsGil5pbgcXpMVY0xU7dDJS_I2pX1peRm_IZdCtpIr1a6I20WYk1uSDzP1M70PIdN7PE5g8YBzpi5Eug4xe0tvfUpocyE_0t0j0u1uS9fjMmW6gTh6sHS7xJ8YT_QWMhhISNczTKfk0zW5cDAlvHmpV-Thy-fd5lt19-Pr9836rrKia3NlrFEKTd8qJVljwfUt8NGBaXrmZDeOnHWigwGkwlb0xvSSi8FaNI6zXqG4Iu_Pe48x_FowZX3wyeI0wYxhSZor2fJBSNEUtD-jNoaUIjp9jP4A8aQbpp8t673-Z1k_W9ZM6GK5RN-9XFnMAce_wT9aC_DpDGD59clj1Ml6nC2OPhaDegz-_1d-A4pLlE0</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>Hemli, Jonathan M.</creator><creator>Ducca, Emma L.</creator><creator>Chaplin, William F.</creator><creator>Arader, Lindsay L.</creator><creator>Scheinerman, S. Jacob</creator><creator>Lesser, Martin L.</creator><creator>Ahn, Seungjun</creator><creator>Mihelis, Efstathia A.</creator><creator>Jahn, Lynda A.</creator><creator>Patel, Nirav C.</creator><creator>Brinster, Derek R.</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20221201</creationdate><title>Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis</title><author>Hemli, Jonathan M. ; Ducca, Emma L. ; Chaplin, William F. ; Arader, Lindsay L. ; Scheinerman, S. Jacob ; Lesser, Martin L. ; Ahn, Seungjun ; Mihelis, Efstathia A. ; Jahn, Lynda A. ; Patel, Nirav C. ; Brinster, Derek R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-bcb66eb8466501caf84a2dfab180f57dd20737a9a56e438bb85239ccebf2086e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hemli, Jonathan M.</creatorcontrib><creatorcontrib>Ducca, Emma L.</creatorcontrib><creatorcontrib>Chaplin, William F.</creatorcontrib><creatorcontrib>Arader, Lindsay L.</creatorcontrib><creatorcontrib>Scheinerman, S. Jacob</creatorcontrib><creatorcontrib>Lesser, Martin L.</creatorcontrib><creatorcontrib>Ahn, Seungjun</creatorcontrib><creatorcontrib>Mihelis, Efstathia A.</creatorcontrib><creatorcontrib>Jahn, Lynda A.</creatorcontrib><creatorcontrib>Patel, Nirav C.</creatorcontrib><creatorcontrib>Brinster, Derek R.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hemli, Jonathan M.</au><au>Ducca, Emma L.</au><au>Chaplin, William F.</au><au>Arader, Lindsay L.</au><au>Scheinerman, S. Jacob</au><au>Lesser, Martin L.</au><au>Ahn, Seungjun</au><au>Mihelis, Efstathia A.</au><au>Jahn, Lynda A.</au><au>Patel, Nirav C.</au><au>Brinster, Derek R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2022-12-01</date><risdate>2022</risdate><volume>114</volume><issue>6</issue><spage>2149</spage><epage>2156</epage><pages>2149-2156</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Transfusion in acute aortic syndromes has been studied in a limited fashion. We sought to describe contemporary transfusion practice for root replacement in acute (Stanford) type A aortic dissection.
The Society of Thoracic Surgeons Adult Cardiac Surgery Database was interrogated to identify patients who underwent primary aortic root replacement for acute (Stanford) type A aortic dissection (July 2014 to June 2017). Patients (n = 1558) were stratified by type of root replacement. Multivariate regression was used to determine those variables associated with transfusion and postoperative morbidity.
Transfusion was required in 90.5% of cases (n = 1410). Operative mortality for all patients was 17.3% (261 deaths). Intraoperative red blood cell transfusion portended reduced short-term survival (odds ratio [OR] 2.00, P = .025). Massive postoperative transfusion was associated with prolonged ventilation (OR 13.47, P < .001), sepsis (OR 4.13, P < .001), and new dialysis-dependent renal failure (OR 2.43, P < .001). Women were more likely to require transfusion (OR 3.03, P < .001), as were patients who had coronary artery bypass (OR 1.57, P = .009), and those in shock (OR 2.27, P < .001). Valve-sparing aortic root replacement was associated with reduced transfusion requirements vs composite roots. Institutional case volume was not appreciably correlated with transfusion.
Most patients undergoing root replacement for aortic dissection require blood products. Composite root replacement is associated with a greater likelihood of transfusion than a valve-sparing operation. Transfusion independently foreshadows greater operative mortality.
[Display omitted]</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>35452664</pmid><doi>10.1016/j.athoracsur.2022.03.068</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-4975 |
| ispartof | The Annals of thoracic surgery, 2022-12, Vol.114 (6), p.2149-2156 |
| issn | 0003-4975 1552-6259 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2654293531 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| title | Transfusion in Root Replacement for Aortic Dissection: The STS Adult Cardiac Surgery Database Analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T02%3A34%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Transfusion%20in%20Root%20Replacement%20for%20Aortic%20Dissection:%20The%20STS%20Adult%20Cardiac%20Surgery%20Database%20Analysis&rft.jtitle=The%20Annals%20of%20thoracic%20surgery&rft.au=Hemli,%20Jonathan%20M.&rft.date=2022-12-01&rft.volume=114&rft.issue=6&rft.spage=2149&rft.epage=2156&rft.pages=2149-2156&rft.issn=0003-4975&rft.eissn=1552-6259&rft_id=info:doi/10.1016/j.athoracsur.2022.03.068&rft_dat=%3Cproquest_cross%3E2654293531%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2654293531&rft_id=info:pmid/35452664&rft_els_id=S0003497522005197&rfr_iscdi=true |