Correlation and colocalization of HIF-1α and pimonidazole staining for hypoxia in laryngeal squamous cell carcinomas: A digital, single-cell-based analysis

•Analysis of hypoxia markers in laryngeal cancer using open-source software is feasible.•We found no significant correlation between HIF-1α and PIMO positive cell percentages.•There is a moderate correlation between the number of HIF-1α and PIMO positive regions.•The overlap between HIF-1α and PIMO...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2022-05, Vol.128, p.105862-105862, Article 105862
Hauptverfasser:	Swartz, Justin E., Smits, Hilde J.G., Philippens, Marielle E.P., de Bree, Remco, H.A.M. Kaanders, Johannes, Willems, Stefan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - metabolism Biomarkers, Tumor - metabolism Cell Hypoxia Head and Neck Neoplasms Humans Hypoxia Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Image Processing, Computer-Assisted Laryngeal Neoplasms - pathology Microscopy Nitroimidazoles Pathology Prognosis Reproducibility of Results Squamous Cell Carcinoma of Head and Neck Staining and Labeling
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!