Proarrhythmic Effects of Sympathetic Activation Are Mitigated by Vagal Nerve Stimulation in Infarcted Hearts

The goal of this study was to evaluate whether intermittent VNS reduces electrical heterogeneities and arrhythmia inducibility during sympathoexcitation. Sympathoexcitation increases the risk of ventricular tachyarrhythmias (VT). Vagal nerve stimulation (VNS) has been antiarrhythmic in the setting o...

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Veröffentlicht in:	JACC. Clinical electrophysiology 2022-04, Vol.8 (4), p.513-525
Hauptverfasser:	Hoang, Jonathan D., Yamakawa, Kentaro, Rajendran, Pradeep S., Chan, Christopher A., Yagishita, Daigo, Nakamura, Keijiro, Lux, Robert L., Vaseghi, Marmar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrhythmias, Cardiac Cicatrix dispersion Heart Heart Rate - physiology Humans myocardial infarction Myocardial Infarction - complications Myocardial Infarction - therapy neuromodulation Swine sympathetic Tachycardia, Ventricular - therapy vagal nerve stimulation Vagus Nerve Stimulation ventricular arrhythmias
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