Functional characterization of a novel violacein biosynthesis operon from Janthinobacterium sp. B9-8

Violacein is a secondary metabolite mainly produced by Gram-negative bacteria that is formed from tryptophan by five enzymes encoded by a single operon. It is a broad-spectrum antibacterial pigment with various important biological activities such as anti-tumor, antiviral, and antioxidative effects....

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Veröffentlicht in:	Applied microbiology and biotechnology 2022-04, Vol.106 (8), p.2903-2916
Hauptverfasser:	Xu, Xian, Chu, Xiaoting, Du, Bangmian, Huang, Chunyan, Xie, Chengjia, Zhang, Zhidong, Jiang, Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Bacteria Biomedical and Life Sciences Biosynthesis Biotechnological Products and Process Engineering Biotechnology E coli Escherichia coli Escherichia coli - genetics Escherichia coli - metabolism Fermentation Genomes Gram-negative bacteria Indoles - metabolism Inoculum Life Sciences Metabolites Microbial Genetics and Genomics Microbiology Microorganisms Natural products Operon Oxalobacteraceae - genetics Physiological aspects Plasmids Proteobacteria Tryptophan Tumors Violacein
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