Perioperative cell-free DNA trends predict recurrence of non-metastatic colorectal cancer significantly earlier than CEA trends over the first 2 years post-operatively in stage II and stage III colon cancer

Purpose We aimed to compare the diagnostic accuracy of perioperative ΔcfDNA to ΔCEA (over the first 2 years post-operatively) for identifying disease recurrence in colon cancer. Methods Patients presenting for elective resection for colon cancer with curative intent were screened for inclusion. Peri...

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Veröffentlicht in:	International journal of colorectal disease 2022-05, Vol.37 (5), p.1119-1126
Hauptverfasser:	Fleming, Christina A., Jordan, Patrick, O’Leary, Donal P., Corrigan, Mark A., Wang, J. H., Redmond, H. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Carcinoembryonic Antigen Cell-Free Nucleic Acids Colonic Neoplasms - genetics Colonic Neoplasms - surgery Colorectal cancer Colorectal Neoplasms - surgery Development and progression Diseases DNA Female Gastroenterology Genetic aspects Hepatology Humans Internal Medicine Male Medicine Medicine & Public Health Metastasis Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - genetics Oncology, Experimental Original Article Pilot Projects Proctology Prognosis Relapse Surgery
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