Association of plaque enhancement on vessel wall MRI and the phosphodiesterase 4D variant with stroke recurrence in patients with symptomatic intracranial atherosclerosis

Purpose Vessel wall MRI (VW-MRI) can be used to evaluate the nature of intracranial atherosclerosis (ICAS) plaque in vivo. Phosphodiesterase 4D (PDE4D) participates in stroke development. This study aims to explore the value of VW-MRI findings and the PDE4D gene variant in predicting stroke recurren...

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Veröffentlicht in:	Neuroradiology 2022-09, Vol.64 (9), p.1781-1794
Hauptverfasser:	Xu, Chuanhui, Qin, Jun, Yu, Jinhui, Sun, Yan, Hu, Dongmin, Wu, Gang, Li, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Atherosclerosis Cyclic Nucleotide Phosphodiesterases, Type 4 - genetics Diagnostic Neuroradiology Health risks Humans Imaging In vivo methods and tests Intracranial Arteriosclerosis - complications Intracranial Arteriosclerosis - diagnostic imaging Intracranial Arteriosclerosis - genetics Ischemia Ischemic Stroke Magnetic Resonance Imaging Medicine Medicine & Public Health Multivariate analysis Neurology Neuroradiology Neurosciences Neurosurgery Nucleotides Phosphodiesterase Plaque, Atherosclerotic - complications Plaque, Atherosclerotic - diagnostic imaging Radiology Risk analysis Risk factors Single-nucleotide polymorphism Statistical models Stroke Stroke - complications Stroke - diagnostic imaging Stroke - genetics Vessels
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