Streamlined Alkylation via Nickel-Hydride-Catalyzed Hydrocarbonation of Alkenes

Compounds rich in sp3-hybridized carbons are desirable in drug discovery. Nickel-catalyzed hydrocarbonation of alkenes is a potentially efficient method to synthesize these compounds. By using abundant, readily available, and stable alkenes as pro-nucleophiles, these reactions can have broad scope a...

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Veröffentlicht in:	Journal of the American Chemical Society 2022-04, Vol.144 (16), p.7015-7029
Hauptverfasser:	Zhang, Zhikun, Bera, Srikrishna, Fan, Chao, Hu, Xile
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes Alkylation Catalysis Nickel
Online-Zugang:	Volltext
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