Breaching B cell tolerance in the tumor microenvironment

The immune system employs complex tolerance mechanisms in order to avoid harmful autoimmunity, yet autoantibodies are frequently observed in cancer. In a paper in Cell, Mazor et al. report that autoantibodies produced by tumor-infiltrating B cells in human ovarian cancer frequently recognize the sel...

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Veröffentlicht in:	Cancer cell 2022-04, Vol.40 (4), p.356-358
Hauptverfasser:	Banville, Allyson C., Nelson, Brad H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies Autoimmunity B-Lymphocytes Humans Immune Tolerance Tumor Microenvironment
Online-Zugang:	Volltext
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