Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3

Objective To investigate the effects of composite Sophora colon-soluble Capsule (CSCC) on gut microbiota-mediated short-chain fatty acids (SCFAs) production and downstream group 3 innate lymphoid cells (ILC3s) of dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) mice model. Methods The ma...

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Veröffentlicht in:	Chinese journal of integrative medicine 2023-05, Vol.29 (5), p.424-433
Hauptverfasser:	Chen, Ming-jun, Feng, Yang, Gao, Lu, Lin, Ming-xiong, Wang, Shi-da, Tong, Zhan-qi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Butyric Acid - metabolism Butyric Acid - pharmacology Butyric Acid - therapeutic use Colitis - chemically induced Colitis - metabolism Colitis - pathology Colitis, Ulcerative - chemically induced Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology Colon Disease Models, Animal Gastrointestinal Microbiome Immunity, Innate Lymphocytes Male Medicine Medicine & Public Health Mice Mice, Inbred C57BL Original Article Sophora
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