Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme

Among the functions exerted by eukaryotic lactate dehydrogenases, it is of importance the generation of lactate in muscles subjected to fatigue or to limited oxygen availability, with both these conditions triggering a decrease of cellular pH. However, the mutual dependence between lactate dehydroge...

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Veröffentlicht in:	Biochimie 2022-08, Vol.199, p.23-35
Hauptverfasser:	Iacovino, Luca Giacinto, Rossi, Martina, Di Stefano, Giuseppina, Rossi, Valentina, Binda, Claudia, Brigotti, Maurizio, Tomaselli, Fabio, Pasti, Alberto Pietro, Dal Piaz, Fabrizio, Cerini, Stefano, Hochkoeppler, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Citrate Krebs cycle Lactate dehydrogenase pH-dependent allostery Rabbit muscle
Online-Zugang:	Volltext
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