Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy

•Finasteride led significant improvement in autism-like behavioral parameters.•Finasteride showed antioxidant and anti-inflammatory effect through Nrf2 modulation.•MR spectroscopy revealed protective effect of finasteride on energy metabolism.•Finasteride showed neuroprotective effect on Purkinje ce...

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Veröffentlicht in:	Neuroscience letters 2022-05, Vol.779, p.136622-136622, Article 136622
Hauptverfasser:	Sever, I.H., Ozkul, B., Bozkurt, M.F., Erbas, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autism Finasteride Lactate MR spectroscopy Nrf2 Propionic acid
Online-Zugang:	Volltext
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