Quantification and toxicokinetics of paraquat in mouse plasma and lung tissues by internal standard surface-enhanced Raman spectroscopy

Paraquat is a quaternary ammonium herbicide with an excellent herbicidal effect but is highly toxic to human and animals. Although prohibited by many countries, paraquat intoxication occurred occasionally and caused severe consequences. Rapid and accurate determination of paraquat concentration in i...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2022-03, Vol.414 (7), p.2371-2383
Hauptverfasser:	Qin, Luyuan, Zhang, Xiaomin, Wu, Jianfeng, Zhang, Wenpeng, Lu, Xiaoxia, Sun, Hao, Zhang, Jinsong, Guo, Lei, Xie, Jianwei
Format:	Artikel
Sprache:	eng
Schlagworte:	absorption Ammonium Analysis Analytical Chemistry Animals Biochemistry blood Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Food Science Herbicides Herbicides - toxicity Humans Identification and classification Intoxication Laboratory Medicine Lung Lungs Methods Mice Molecular weight Monitoring/Environmental Analysis Paraquat Paraquat - toxicity pharmacokinetics Plasma poisoning prognosis Properties quantitative analysis quaternary ammonium compounds Raman spectroscopy Research Paper Spectroscopy Spectrum analysis Spectrum Analysis, Raman toxicity Toxicokinetics
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