Single Particle Cryo-Electron Microscopy: From Sample to Structure

Cryo-electron microscopy (cryoEM) is a powerful technique for structure determination of macromolecular complexes, via single particle analysis (SPA). The overall process involves i) vitrifying the specimen in a thin film supported on a cryoEM grid; ii) screening the specimen to assess particle dist...

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Veröffentlicht in:	Journal of visualized experiments 2021-05 (171)
Hauptverfasser:	White, Joshua B.R., Maskell, Daniel P., Howe, Andrew, Harrow, Martin, Clare, Daniel K., Siebert, C. Alistair, Hesketh, Emma L., Thompson, Rebecca F.
Format:	Artikel
Sprache:	eng
Schlagworte:	cryo-electron microscopy data collection films (materials) ice
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