Abdominal Sarcoidosis Mimicking Pancreatic Adenocarcinoma
Sarcoidosis is a chronic, granulomatous, autoinflammatory disease that affects different parts of the body. Pulmonary manifestations are described in the majority of cases, with pancreatic involvement being
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Veröffentlicht in: | The American surgeon 2022-08, Vol.88 (8), p.1888-1890 |
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creator | Favors, Lauren Koffron, Julie |
description | Sarcoidosis is a chronic, granulomatous, autoinflammatory disease that affects different parts of the body. Pulmonary manifestations are described in the majority of cases, with pancreatic involvement being |
doi_str_mv | 10.1177/00031348221084963 |
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Pulmonary manifestations are described in the majority of cases, with pancreatic involvement being <1-5%. The initial reports of pancreatic sarcoidosis were detected on autopsy. A review of the literature revealed that the majority of patients with pancreatic sarcoidosis initially presented with a clinical presentation identical to pancreatic malignancy. We describe the case of a male with a history of chronic pancreatitis and alcoholism who underwent pancreaticoduodenectomy given the concern for pancreatic denocarcinoma, and was found to have isolated pancreatic sarcoidosis. This case illustrates the difficulty in diagnosing the etiology of pancreatic masses pre-operatively leading to the majority of cases getting definitive diagnosis after operative exploration. We suggest that there needs to be further delineation of this disease process in order to determine the best treatment options for patients presenting with pancreatic disease.</description><identifier>ISSN: 0003-1348</identifier><identifier>EISSN: 1555-9823</identifier><identifier>DOI: 10.1177/00031348221084963</identifier><identifier>PMID: 35389292</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Abdomen ; Adenocarcinoma ; Adenocarcinoma - diagnosis ; Alcoholism ; Autopsies ; Autopsy ; Bile ducts ; Biopsy ; Cancer ; Diagnosis, Differential ; Etiology ; Granulomas ; Humans ; Inflammation ; Inflammatory diseases ; Literature reviews ; Lymphatic system ; Male ; Malignancy ; Pancreas ; Pancreatic cancer ; Pancreatic diseases ; Pancreatic Neoplasms ; Pancreatic Neoplasms - diagnosis ; Pancreaticoduodenectomy ; Pancreatitis ; Patients ; Sarcoidosis ; Sarcoidosis - diagnosis ; Steroids ; Tomography, X-Ray Computed</subject><ispartof>The American surgeon, 2022-08, Vol.88 (8), p.1888-1890</ispartof><rights>The Author(s) 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c320t-11e134097d3a522c426af5eaffb49fc9fe599ac4609a5185c1a48eec8df74c1b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/00031348221084963$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/00031348221084963$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,777,781,21800,27905,27906,43602,43603</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35389292$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Favors, Lauren</creatorcontrib><creatorcontrib>Koffron, Julie</creatorcontrib><title>Abdominal Sarcoidosis Mimicking Pancreatic Adenocarcinoma</title><title>The American surgeon</title><addtitle>Am Surg</addtitle><description>Sarcoidosis is a chronic, granulomatous, autoinflammatory disease that affects different parts of the body. Pulmonary manifestations are described in the majority of cases, with pancreatic involvement being <1-5%. The initial reports of pancreatic sarcoidosis were detected on autopsy. A review of the literature revealed that the majority of patients with pancreatic sarcoidosis initially presented with a clinical presentation identical to pancreatic malignancy. We describe the case of a male with a history of chronic pancreatitis and alcoholism who underwent pancreaticoduodenectomy given the concern for pancreatic denocarcinoma, and was found to have isolated pancreatic sarcoidosis. This case illustrates the difficulty in diagnosing the etiology of pancreatic masses pre-operatively leading to the majority of cases getting definitive diagnosis after operative exploration. We suggest that there needs to be further delineation of this disease process in order to determine the best treatment options for patients presenting with pancreatic disease.</description><subject>Abdomen</subject><subject>Adenocarcinoma</subject><subject>Adenocarcinoma - diagnosis</subject><subject>Alcoholism</subject><subject>Autopsies</subject><subject>Autopsy</subject><subject>Bile ducts</subject><subject>Biopsy</subject><subject>Cancer</subject><subject>Diagnosis, Differential</subject><subject>Etiology</subject><subject>Granulomas</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Inflammatory diseases</subject><subject>Literature reviews</subject><subject>Lymphatic system</subject><subject>Male</subject><subject>Malignancy</subject><subject>Pancreas</subject><subject>Pancreatic cancer</subject><subject>Pancreatic diseases</subject><subject>Pancreatic Neoplasms</subject><subject>Pancreatic Neoplasms - diagnosis</subject><subject>Pancreaticoduodenectomy</subject><subject>Pancreatitis</subject><subject>Patients</subject><subject>Sarcoidosis</subject><subject>Sarcoidosis - diagnosis</subject><subject>Steroids</subject><subject>Tomography, X-Ray Computed</subject><issn>0003-1348</issn><issn>1555-9823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1LAzEQhoMotlZ_gBcpePGyNZ-7ybGIX1BRUM_LbDYpqbubmnQP_nuztCoonoZhnvedmRehU4JnhBTFJcaYEcYlpQRLrnK2h8ZECJEpSdk-Gg_zbABG6CjGVWp5LsghGjHBpKKKjpGaV7VvXQfN9BmC9q720cXpg2udfnPdcvoEnQ4GNk5P57XpvE6U63wLx-jAQhPNya5O0OvN9cvVXbZ4vL2_mi8yzSjeZISYdAFWRc1AUKo5zcEKA9ZWXFmtrBFKgeY5ViCIFJoAl8ZoWduCa1KxCbrY-q6Df-9N3JSti9o0DXTG97GkOZc4p0LmCT3_ha58H9JvAyVl2lFImSiypXTwMQZjy3VwLYSPkuByyLX8k2vSnO2c-6o19bfiK8gEzLZAhKX5Wfu_4ydJ735p</recordid><startdate>202208</startdate><enddate>202208</enddate><creator>Favors, Lauren</creator><creator>Koffron, Julie</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>4T-</scope><scope>4U-</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>202208</creationdate><title>Abdominal Sarcoidosis Mimicking Pancreatic Adenocarcinoma</title><author>Favors, Lauren ; Koffron, Julie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-11e134097d3a522c426af5eaffb49fc9fe599ac4609a5185c1a48eec8df74c1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdomen</topic><topic>Adenocarcinoma</topic><topic>Adenocarcinoma - diagnosis</topic><topic>Alcoholism</topic><topic>Autopsies</topic><topic>Autopsy</topic><topic>Bile ducts</topic><topic>Biopsy</topic><topic>Cancer</topic><topic>Diagnosis, Differential</topic><topic>Etiology</topic><topic>Granulomas</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Inflammatory diseases</topic><topic>Literature reviews</topic><topic>Lymphatic system</topic><topic>Male</topic><topic>Malignancy</topic><topic>Pancreas</topic><topic>Pancreatic cancer</topic><topic>Pancreatic diseases</topic><topic>Pancreatic Neoplasms</topic><topic>Pancreatic Neoplasms - diagnosis</topic><topic>Pancreaticoduodenectomy</topic><topic>Pancreatitis</topic><topic>Patients</topic><topic>Sarcoidosis</topic><topic>Sarcoidosis - diagnosis</topic><topic>Steroids</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Favors, Lauren</creatorcontrib><creatorcontrib>Koffron, Julie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American surgeon</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Favors, Lauren</au><au>Koffron, Julie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abdominal Sarcoidosis Mimicking Pancreatic Adenocarcinoma</atitle><jtitle>The American surgeon</jtitle><addtitle>Am Surg</addtitle><date>2022-08</date><risdate>2022</risdate><volume>88</volume><issue>8</issue><spage>1888</spage><epage>1890</epage><pages>1888-1890</pages><issn>0003-1348</issn><eissn>1555-9823</eissn><abstract>Sarcoidosis is a chronic, granulomatous, autoinflammatory disease that affects different parts of the body. Pulmonary manifestations are described in the majority of cases, with pancreatic involvement being <1-5%. The initial reports of pancreatic sarcoidosis were detected on autopsy. A review of the literature revealed that the majority of patients with pancreatic sarcoidosis initially presented with a clinical presentation identical to pancreatic malignancy. We describe the case of a male with a history of chronic pancreatitis and alcoholism who underwent pancreaticoduodenectomy given the concern for pancreatic denocarcinoma, and was found to have isolated pancreatic sarcoidosis. This case illustrates the difficulty in diagnosing the etiology of pancreatic masses pre-operatively leading to the majority of cases getting definitive diagnosis after operative exploration. We suggest that there needs to be further delineation of this disease process in order to determine the best treatment options for patients presenting with pancreatic disease.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>35389292</pmid><doi>10.1177/00031348221084963</doi><tpages>3</tpages></addata></record> |
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subjects | Abdomen Adenocarcinoma Adenocarcinoma - diagnosis Alcoholism Autopsies Autopsy Bile ducts Biopsy Cancer Diagnosis, Differential Etiology Granulomas Humans Inflammation Inflammatory diseases Literature reviews Lymphatic system Male Malignancy Pancreas Pancreatic cancer Pancreatic diseases Pancreatic Neoplasms Pancreatic Neoplasms - diagnosis Pancreaticoduodenectomy Pancreatitis Patients Sarcoidosis Sarcoidosis - diagnosis Steroids Tomography, X-Ray Computed |
title | Abdominal Sarcoidosis Mimicking Pancreatic Adenocarcinoma |
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