A rare frameshift mutation in SYCP1 is associated with human male infertility

Abstract Proper assembly of the synaptonemal complex is essential for successful meiosis, and impairments in the process lead to infertility. Meiotic transverse filament proteins encoded by the SYCP1 (synaptonemal complex protein 1) gene are one of the main components of the synaptonemal complex and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular human reproduction 2022-04, Vol.28 (4)
Hauptverfasser:	Nabi, Soheila, Askari, Masomeh, Rezaei-Gazik, Maryam, Salehi, Najmeh, Almadani, Navid, Tahamtani, Yaser, Totonchi, Mehdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA-Binding Proteins - genetics Frameshift Mutation Humans Infertility, Male - genetics Male Meiosis Mice Nuclear Proteins - genetics Oligospermia - genetics Synaptonemal Complex - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!