Blocking CD47 promotes antitumour immunity through CD103+ dendritic cell–NK cell axis in murine hepatocellular carcinoma model

The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs and the potential crosstalk between DCs and natural killer (NK) cells in the hepatocellular carcinoma (HCC) microenvironment after CD47 blockad...

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Veröffentlicht in:	Journal of hepatology 2022-08, Vol.77 (2), p.467-478
Hauptverfasser:	Wang, Shuai, Wu, Qinchuan, Chen, Tianchi, Su, Rong, Pan, Caixu, Qian, Junjie, Huang, Hechen, Yin, Shengyong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen
Format:	Artikel
Sprache:	eng
Schlagworte:	CD103+ dendritic cells CD47 Hepatocellular carcinoma Natural killer cells STING
Online-Zugang:	Volltext
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