Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular docking

Qingfeiyin (QFY) is a common Chinese herbal formula for the treatment of acute lung injury (ALI). However, its mechanisms of action are unclear. In this study, we systematically explored the effects and mechanism of action of QFY in ALI using network pharmacology and molecular docking. Active compou...

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Veröffentlicht in:	Computers in biology and medicine 2022-06, Vol.145, p.105454-105454, Article 105454
Hauptverfasser:	Wang, Ying, Yuan, Yuan, Wang, Wenting, He, Ying, Zhong, Hong, Zhou, Xiaoxia, Chen, Yong, Cai, Xin-Jun, Liu, Li-qin
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Acute lung injury AKT protein Apoptosis Bioavailability Chinese medicine Core protein Datasets Drug screening Gene expression GEO datasets Herbal medicine Hydrogenation Lungs MAP kinase Molecular docking Molecular dynamics Molecular modelling Network pharmacology Oxidative stress Permeability Pharmacology Proteins Qingfeiyin Simulation Software Tissue analysis Traditional Chinese medicine Visualization
Online-Zugang:	Volltext
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