Anti-adipogenic activity of maackiain and ononin is mediated via inhibition of PPARγ in human adipocytes

Obesity is a global health burden for which we do not yet have effective treatments for prevention or therapy. Plants are an invaluable source of bioactive leads possessing anti-adipogenic potential. Ethnopharmacological use of Ononis spinosa L. roots (OSR) for treatment of obesity and metabolic dis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedicine & pharmacotherapy 2022-05, Vol.149, p.112908-112908, Article 112908
Hauptverfasser:	Mladenova, Saveta G., Savova, Martina S., Marchev, Andrey S., Ferrante, Claudio, Orlando, Giustino, Wabitsch, Martin, Georgiev, Milen I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - drug effects Adipogenesis Adiponectin - metabolism Anti-Obesity Agents - pharmacology Glucosides - pharmacology Humans Isoflavones - pharmacology Maackiain Molecular Docking Simulation Obesity Obesity - drug therapy Obesity - metabolism Ononin Ononis spinosa L Phosphatidylinositol 3-Kinases - metabolism PPAR gamma - antagonists & inhibitors PPAR gamma - metabolism PPARγ Pterocarpans - pharmacology Sirtuin 1 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!