Therapeutic implications of sonic hedgehog pathway in metabolic disorders: Novel target for effective treatment

Hedgehog, a developmental morphogen, and its downstream signalling have recently been associated with metabolic control. Sonic hedgehog signalling (Shh) is a significant pathway that regulates various events during the growth and development of embryos. The dysregulation of the Shh pathway has been...

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Veröffentlicht in:	Pharmacological research 2022-05, Vol.179, p.106194-106194, Article 106194
Hauptverfasser:	Garg, Chahat, khan, Heena, Kaur, Amarjot, Singh, Thakur Gurjeet, Sharma, Vivek Kumar, Singh, Sachin Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Canonical and non-canonical pathway Down-Regulation Glucose tolerance Hedgehog Proteins - metabolism Humans Insulin resistance Metabolic diseases Metabolic Diseases - drug therapy Signal Transduction Sonic hedgehog pathway Transforming Growth Factor beta - metabolism
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