Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study

Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin. SOURCE evaluated the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma. We conducted this phase 3, multicentre, randomised, double-blind, placebo-c...

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Veröffentlicht in:	The lancet respiratory medicine 2022-07, Vol.10 (7), p.650-660
Hauptverfasser:	Wechsler, Michael E, Menzies-Gow, Andrew, Brightling, Christopher E, Kuna, Piotr, Korn, Stephanie, Welte, Tobias, Griffiths, Janet M, Sałapa, Kinga, Hellqvist, Åsa, Almqvist, Gun, Lal, Harbans, Kaur, Primal, Skärby, Tor, Colice, Gene, Cambursano, Victor H, Fernandez, Marcelo J, Scherbovsky, Fernando D, Yanez, Anahi, Tolcachier, Alberto J, Stok, Ana M, Verra, Fernando J B, Forster, Karin, Rolke, Mathias, Ludwig-Sengpiel, Andrea, Schmoller, Tibor, Schmidt, Olaf, Milger-Kneidinger, Katrin, Hoffmann, Martin, Temme, Hilke, Linnhoff, Anneliese, Kirschner, Joachim, Rewerska, Barbara, Pisarczyk-Bogacka, Ewa, Haak Lee, Sang, Jae Lee, Byung, Park, Heung-Woo, Park, Jung-Won, Young Lee, Sook, Sook Cho, You, Ho Lee, Kwan, Bavbek, Sevim, Gemicioglu, Bilun, Ediger, Dane, Koca Kalkan, Ilkay, Hanta, Ismail, Yorgancioglu, Arzu, DytyatkovsKa, Yevgeniya, Mostovoy, Yuriy M, Lebed, Kyrylo, Yakovenko, Oleh, Bernstein, David I, Tillinghast, Jeffrey P, Que, Loretta, Madison, Jan, Rambasek, Todd, Shenoy, Kartik, Thompson, Charles A, Chappel, Christopher M, Hudes, Golda, Sorial, Ehab, Kureishy, Shahrukh A, Rehman, Syed M, Lugogo, Njira, Gonzalez, Erika G, Umeh, Fred C, Boren, Eric J, Sigmon, Jason, Ismail, Hummayun, Mohan, Arjun, Bansal, Sandeep, Kaelin, Thomas D
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Sprache:	eng
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