Prediction of the mechanisms of action of Zhibai Dihaung Granule in cisplatin-induced acute kidney injury: A network pharmacology study and experimental validation

Zhibai Dihuang Granule (ZDG) is known as traditional Chinese patent medicine with the functions of “Ziyin decrease internal heat” in Traditional Chinses medicine. In clinical, it is also used to treat various kidney diseases. We aimed to provide a basis for the curative effect of ZDG on acute kidney...

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Veröffentlicht in:	Journal of ethnopharmacology 2022-06, Vol.292, p.115241-115241, Article 115241
Hauptverfasser:	Liu, Zhen, Xu, Ye, Bai, Xinming, Guo, Lvqian, Li, Xinran, Gao, Junling, Teng, Yuou, Yu, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Acute Kidney Injury - drug therapy Animals Cisplatin - toxicity Cisplatin-induced acute kidney injury Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Female Humans Inflammation - drug therapy Male Medicine, Chinese Traditional - methods Molecular Docking Simulation Network Pharmacology Rats Rats, Sprague-Dawley Traditional Chinses medicine Zhibai Dihuang Granule
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