Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice

DNA damage is assumed to accumulate in stem cells over time and their ability to withstand this damage and maintain tissue homeostasis is the key determinant of aging. Nonetheless, relatively few studies have investigated whether DNA damage does indeed accumulate in stem cells and whether this contr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2022-05, Vol.40 (5), p.493-507
Hauptverfasser:	Ren, Jie, Wang, Xianli, Dong, Chuanming, Wang, Guangming, Zhang, Wenjun, Cai, Chunhui, Qian, Minxian, Yang, Danjing, Ling, Bin, Ning, Ke, Mao, Zhiyong, Liu, Baohua, Wang, Tinghua, Xiong, Liuliu, Wang, Wenyuan, Liang, Aibin, Gao, Zhengliang, Xu, Jun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!