Evaluation of the clinical value of automatic online dose restoration for adaptive proton therapy of head and neck cancer

•An online adaptive strategy was compared to not-adaptation of robust clinical plans and offline adaptation.•Not-adapted robustly optimized plans achieved adequate target coverage in up to only 26% of repeated-CTs.•Dose restoration yielded adequate target coverage in 52% of repeated-CTs.•Dose restor...

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Veröffentlicht in:	Radiotherapy and oncology 2022-05, Vol.170, p.190-197
Hauptverfasser:	Borderías-Villarroel, Elena, Taasti, Vicki, Van Elmpt, Wouter, Teruel-Rivas, S., Geets, X., Sterpin, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Head and neck cancer Intensity-modulated proton therapy Inter-fraction variation Online-adaptive proton therapy Robust treatment planning
Online-Zugang:	Volltext
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