Effect of aberrant DNA methylation on cancer stem cell properties

DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of cytosines in position 5 by DNA methyltransferases and has essential roles in cellular function, especially in the transcriptional regulation of embryonic and adult stem cells. Hypomethylation and hypermethylation cause e...

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Veröffentlicht in:	Experimental and molecular pathology 2022-04, Vol.125, p.104757-104757, Article 104757
Hauptverfasser:	Mazloumi, Zeinab, Farahzadi, Raheleh, Rafat, Ali, Dizaji Asl, Khadijeh, Karimipour, Mohammad, Montazer, Majid, Movassaghpour, Ali Akbar, Dehnad, Alireza, Nozad Charoudeh, Hojjatollah
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult cancer stem cells DNA methylation DNA Methylation - genetics Drug resistance Epigenesis, Genetic Gene Expression Regulation, Neoplastic Humans Metastasis Neoplasms - pathology Neoplastic Stem Cells - pathology Self-renewal
Online-Zugang:	Volltext
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