Paclitaxel-Loaded TPGS2k/Gelatin-Grafted Cyclodextrin/Hyaluronic Acid-Grafted Cyclodextrin Nanoparticles for Oral Bioavailability and Targeting Enhancement

The clinical applications of paclitaxel (PTX), a natural compound with broad-spectrum antitumor effects, have been markedly limited owing to its poor oral bioavailability and lack of targeting ability. Recently, several drug carriers, such as TPGS2k, gelatin (Gel), cyclodextrin (CD), and hyaluronic...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2022-06, Vol.111 (6), p.1776-1784
Hauptverfasser:	Zou, Linghui, Zhang, Zhongbin, Feng, Jianfang, Ding, Wenyou, Li, Yanhua, Liang, Dan, Xie, Tanfang, Li, Fang, Li, Yuyang, Chen, Jinqing, Yang, Xu, Tang, Ling, Ding, Wenya
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclodextrin Hyaluronic acid Nanoparticles Oral bioavailability Paclitaxel Targeting TPGS2k
Online-Zugang:	Volltext
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