ABCG2, SCN1A and CYP3A5 genes polymorphism and drug-resistant epilepsy in children: A case-control study

•Pharmacogenetic pathways are one of the important elements that can help clinicians determine medication response and provide more efficient drug therapy, especially in cases of drug resistance.•In this case-control study, we assessed the association between candidate SNPs in three genes (CYP3A5, S...

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Veröffentlicht in:	Seizure (London, England) England), 2022-04, Vol.97, p.58-62
Hauptverfasser:	Mousavi, Seyedeh Farnaz, Hasanpour, Kazem, Nazarzadeh, Milad, Adli, Abolfazl, Bazghandi, Malihe Sadat, Asadi, Alireza, Rad, Abolfazl, Gholami, Omid
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCG2 Adolescent Anticonvulsants - therapeutic use ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics Case-Control Studies Child Child, Preschool CYP3A53 Cytochrome P-450 CYP3A - genetics Drug Resistant Epilepsy - drug therapy Drug Resistant Epilepsy - genetics Drug-resistant Epilepsy Epilepsy - drug therapy Epilepsy - genetics Female Genetic polymorphisms Genotype Humans Infant Iran Male NAV1.1 Voltage-Gated Sodium Channel - genetics Neoplasm Proteins - genetics Polymorphism, Single Nucleotide - genetics SCN1A
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