Penicillin-binding proteins (PBPs) determine antibiotic action in Langmuir monolayers as nanoarchitectonics mimetic membranes of methicillin-resistant Staphylococcus aureus

The membrane of methicillin-resistant Staphylococcus aureus (MRSA) contains penicillin-binding proteins (PBPs) in the phospholipidic bilayer, with the protein PBP2a being linked with the resistance mechanism. In this work we confirm the role of PBP2a with molecular-level information obtained with La...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2022-06, Vol.214, p.112447-112447, Article 112447
Hauptverfasser:	Martins, Beatriz Araújo, Deffune, Elenice, Oliveira Jr, Osvaldo N., Moraes, Marli Leite de
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Antibiotic Bacterial Proteins - metabolism Brewster angle microscope Langmuir film Meropenem Meropenem - metabolism Meropenem - pharmacology Methicillin - pharmacology Methicillin-Resistant Staphylococcus aureus Microbial Sensitivity Tests Model membrane Penicillin-Binding Proteins - metabolism Penicillin-Binding Proteins - pharmacology
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