Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters
The prevalence of vitamin D deficiency varies across countries and few data exist in the adult population in Greece. To assess vitamin D levels in unselected patients from primary care and to investigate possible correlations with clinical, seasonal, and quality-of-life parameters. In this cross-sec...
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| Veröffentlicht in: | Family practice 2022-07, Vol.39 (4), p.678-684 |
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| creator | Bouloukaki, Izolde Markakis, Manolis Pateli, Rodanthi Lyronis, Ioannis Schiza, Sophia Tsiligianni, Ioanna |
| description | The prevalence of vitamin D deficiency varies across countries and few data exist in the adult population in Greece.
To assess vitamin D levels in unselected patients from primary care and to investigate possible correlations with clinical, seasonal, and quality-of-life parameters.
In this cross-sectional study, 389 consecutive patients were included. They were grouped according to vitamin D status as vitamin D deficient (10; OR = 3.769, 95% CI = 0.984-14.443, P = 0.04), and fatigue (FSS >36; OR = 7.157, 95% CI = 0.855-59.877, P = 0.04) showed significant independent associations with vitamin D deficiency in specific subgroups of patients.
A large proportion of patients in primary care had vitamin D deficiency, independently associated with hypertension, sleepiness, depressive symptoms, and fatigue. Further research is needed in order to determine the role of vitamin D in these patients. |
| doi_str_mv | 10.1093/fampra/cmac012 |
| format | Article |
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To assess vitamin D levels in unselected patients from primary care and to investigate possible correlations with clinical, seasonal, and quality-of-life parameters.
In this cross-sectional study, 389 consecutive patients were included. They were grouped according to vitamin D status as vitamin D deficient (<20 ng/mL) and vitamin D sufficient groups (≥20 ng/mL). Demographic, Epworth Sleepiness Scale (ESS), Athens Insomnia Scale (AIS), Beck Depression Inventory (BDI), and Fatigue Severity Scale (FSS) scores were measured and compared between groups.
Vitamin D deficiency (<20 ng/mL) was observed in 50.4% of the cohort. Female gender (76% vs 66%, P = 0.026), obesity (42% vs 26%, P = 0.005), and hypertension (55% vs 43%, P = 0.023) were higher in the vitamin D deficiency group compared with the group without deficiency. After multiparametric adjustments (for age, gender, obesity, comorbidities, and seasonality), hypertension (odds ratio [OR] = 2.338, 95% confidence interval [CI] = 1.257-4.349, P = 0.007), excessive daytime sleepiness (ESS >10; OR = 3.345, 95% CI = 1.124-9.948, P = 0.029), depressive symptoms (BDI >10; OR = 3.769, 95% CI = 0.984-14.443, P = 0.04), and fatigue (FSS >36; OR = 7.157, 95% CI = 0.855-59.877, P = 0.04) showed significant independent associations with vitamin D deficiency in specific subgroups of patients.
A large proportion of patients in primary care had vitamin D deficiency, independently associated with hypertension, sleepiness, depressive symptoms, and fatigue. Further research is needed in order to determine the role of vitamin D in these patients.</description><identifier>ISSN: 1460-2229</identifier><identifier>EISSN: 1460-2229</identifier><identifier>DOI: 10.1093/fampra/cmac012</identifier><identifier>PMID: 35325110</identifier><language>eng</language><publisher>England</publisher><ispartof>Family practice, 2022-07, Vol.39 (4), p.678-684</ispartof><rights>The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c295t-de6d452e939f722f31800681241a317dd366cc0dc1532cc18eed386488e26b613</citedby><cites>FETCH-LOGICAL-c295t-de6d452e939f722f31800681241a317dd366cc0dc1532cc18eed386488e26b613</cites><orcidid>0000-0001-7922-7491 ; 0000-0002-5224-7692 ; 0000-0001-5903-3550</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35325110$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bouloukaki, Izolde</creatorcontrib><creatorcontrib>Markakis, Manolis</creatorcontrib><creatorcontrib>Pateli, Rodanthi</creatorcontrib><creatorcontrib>Lyronis, Ioannis</creatorcontrib><creatorcontrib>Schiza, Sophia</creatorcontrib><creatorcontrib>Tsiligianni, Ioanna</creatorcontrib><title>Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters</title><title>Family practice</title><addtitle>Fam Pract</addtitle><description>The prevalence of vitamin D deficiency varies across countries and few data exist in the adult population in Greece.
To assess vitamin D levels in unselected patients from primary care and to investigate possible correlations with clinical, seasonal, and quality-of-life parameters.
In this cross-sectional study, 389 consecutive patients were included. They were grouped according to vitamin D status as vitamin D deficient (<20 ng/mL) and vitamin D sufficient groups (≥20 ng/mL). Demographic, Epworth Sleepiness Scale (ESS), Athens Insomnia Scale (AIS), Beck Depression Inventory (BDI), and Fatigue Severity Scale (FSS) scores were measured and compared between groups.
Vitamin D deficiency (<20 ng/mL) was observed in 50.4% of the cohort. Female gender (76% vs 66%, P = 0.026), obesity (42% vs 26%, P = 0.005), and hypertension (55% vs 43%, P = 0.023) were higher in the vitamin D deficiency group compared with the group without deficiency. After multiparametric adjustments (for age, gender, obesity, comorbidities, and seasonality), hypertension (odds ratio [OR] = 2.338, 95% confidence interval [CI] = 1.257-4.349, P = 0.007), excessive daytime sleepiness (ESS >10; OR = 3.345, 95% CI = 1.124-9.948, P = 0.029), depressive symptoms (BDI >10; OR = 3.769, 95% CI = 0.984-14.443, P = 0.04), and fatigue (FSS >36; OR = 7.157, 95% CI = 0.855-59.877, P = 0.04) showed significant independent associations with vitamin D deficiency in specific subgroups of patients.
A large proportion of patients in primary care had vitamin D deficiency, independently associated with hypertension, sleepiness, depressive symptoms, and fatigue. Further research is needed in order to determine the role of vitamin D in these patients.</description><issn>1460-2229</issn><issn>1460-2229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpNkEtPwzAQhC0EoqVw5Yh85ECo106chBsqT6kSF-AaufZGGDmP2i6o_55UDYjTzkozI81HyDmwa2ClmNeq6b2a60ZpBvyATCGVLOGcl4f_9ISchPDJGMvzLD8mE5EJngGwKenebVSNbekddfiFLtBB9942ym-pVh5pr6LFNoYbqjvv0Q1v1wb6beMH1c62Vit3RQOq0LU7pVpD1xvlbNwmXZ04W-86vGowog-n5KhWLuDZeGfk7eH-dfGULF8enxe3y0TzMouJQWnSjGMpyjrnvBZQMCYL4CkoAbkxQkqtmdEwLNEaCkQjCpkWBXK5kiBm5HLf2_tuvcEQq8YGjc6pFrtNqLhMUwbAQQzW671V-y4Ej3U17q-AVTvI1R5yNUIeAhdj92bVoPmz_1IVP7sOetA</recordid><startdate>20220719</startdate><enddate>20220719</enddate><creator>Bouloukaki, Izolde</creator><creator>Markakis, Manolis</creator><creator>Pateli, Rodanthi</creator><creator>Lyronis, Ioannis</creator><creator>Schiza, Sophia</creator><creator>Tsiligianni, Ioanna</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7922-7491</orcidid><orcidid>https://orcid.org/0000-0002-5224-7692</orcidid><orcidid>https://orcid.org/0000-0001-5903-3550</orcidid></search><sort><creationdate>20220719</creationdate><title>Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters</title><author>Bouloukaki, Izolde ; Markakis, Manolis ; Pateli, Rodanthi ; Lyronis, Ioannis ; Schiza, Sophia ; Tsiligianni, Ioanna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c295t-de6d452e939f722f31800681241a317dd366cc0dc1532cc18eed386488e26b613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bouloukaki, Izolde</creatorcontrib><creatorcontrib>Markakis, Manolis</creatorcontrib><creatorcontrib>Pateli, Rodanthi</creatorcontrib><creatorcontrib>Lyronis, Ioannis</creatorcontrib><creatorcontrib>Schiza, Sophia</creatorcontrib><creatorcontrib>Tsiligianni, Ioanna</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Family practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bouloukaki, Izolde</au><au>Markakis, Manolis</au><au>Pateli, Rodanthi</au><au>Lyronis, Ioannis</au><au>Schiza, Sophia</au><au>Tsiligianni, Ioanna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters</atitle><jtitle>Family practice</jtitle><addtitle>Fam Pract</addtitle><date>2022-07-19</date><risdate>2022</risdate><volume>39</volume><issue>4</issue><spage>678</spage><epage>684</epage><pages>678-684</pages><issn>1460-2229</issn><eissn>1460-2229</eissn><abstract>The prevalence of vitamin D deficiency varies across countries and few data exist in the adult population in Greece.
To assess vitamin D levels in unselected patients from primary care and to investigate possible correlations with clinical, seasonal, and quality-of-life parameters.
In this cross-sectional study, 389 consecutive patients were included. They were grouped according to vitamin D status as vitamin D deficient (<20 ng/mL) and vitamin D sufficient groups (≥20 ng/mL). Demographic, Epworth Sleepiness Scale (ESS), Athens Insomnia Scale (AIS), Beck Depression Inventory (BDI), and Fatigue Severity Scale (FSS) scores were measured and compared between groups.
Vitamin D deficiency (<20 ng/mL) was observed in 50.4% of the cohort. Female gender (76% vs 66%, P = 0.026), obesity (42% vs 26%, P = 0.005), and hypertension (55% vs 43%, P = 0.023) were higher in the vitamin D deficiency group compared with the group without deficiency. After multiparametric adjustments (for age, gender, obesity, comorbidities, and seasonality), hypertension (odds ratio [OR] = 2.338, 95% confidence interval [CI] = 1.257-4.349, P = 0.007), excessive daytime sleepiness (ESS >10; OR = 3.345, 95% CI = 1.124-9.948, P = 0.029), depressive symptoms (BDI >10; OR = 3.769, 95% CI = 0.984-14.443, P = 0.04), and fatigue (FSS >36; OR = 7.157, 95% CI = 0.855-59.877, P = 0.04) showed significant independent associations with vitamin D deficiency in specific subgroups of patients.
A large proportion of patients in primary care had vitamin D deficiency, independently associated with hypertension, sleepiness, depressive symptoms, and fatigue. Further research is needed in order to determine the role of vitamin D in these patients.</abstract><cop>England</cop><pmid>35325110</pmid><doi>10.1093/fampra/cmac012</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-7922-7491</orcidid><orcidid>https://orcid.org/0000-0002-5224-7692</orcidid><orcidid>https://orcid.org/0000-0001-5903-3550</orcidid></addata></record> |
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| title | Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters |
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