Genetically Engineered Mesenchymal Stem Cell Therapy Against Murine Experimental Autoimmune Encephalomyelitis

We used recombinant interleukin 23 receptor (RIL-23R)-engineered mesenchymal stem cells (MSCs) to study its therapeutic role in enhancing inflammation of nervous tissue in the mouse model (EAE) of multiple sclerosis (MS). Recombinant IL-23 receptor construct was designed to enter MSCs. The bioactivi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular neurobiology 2022-06, Vol.59 (6), p.3449-3457
Hauptverfasser:	Rostami, Masoumeh, Haidari, Kamran, Amini, Hossein, Shahbazi, Majid
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune diseases Biological activity Biomedical and Life Sciences Biomedicine CD4 antigen Cell Biology Cell culture Cell therapy Demyelination Experimental allergic encephalomyelitis Genetic engineering Inflammation Interleukin 23 Lymphocytes T Mesenchymal stem cells mRNA Multiple sclerosis Myelination Neurobiology Neurology Neurosciences Stem cell transplantation Stem cells Substantia alba Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!