Multimodal magnetic resonance imaging quantification of gray matter alterations in relapsing‐remitting multiple sclerosis and neuromyelitis optica spectrum disorder

Herein, we combined neurite orientation dispersion and density imaging (NODDI) and synthetic magnetic resonance imaging (SyMRI) to evaluate the spatial distribution and extent of gray matter (GM) microstructural alterations in patients with relapsing‐remitting multiple sclerosis (RRMS) and neuromyel...

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Veröffentlicht in:	Journal of neuroscience research 2022-07, Vol.100 (7), p.1395-1412
Hauptverfasser:	Andica, Christina, Hagiwara, Akifumi, Yokoyama, Kazumasa, Kato, Shimpei, Uchida, Wataru, Nishimura, Yuma, Fujita, Shohei, Kamagata, Koji, Hori, Masaaki, Tomizawa, Yuji, Hattori, Nobutaka, Aoki, Shigeki
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Adult Age Aged Antibodies Cerebellum demyelination Density diffusion tensor imaging Diffusion Tensor Imaging - methods Dispersion Female Females Gray Matter - diagnostic imaging Gray Matter - pathology Humans Magnetic Resonance Imaging Male Males Medical imaging Middle Aged Multiple sclerosis Multiple Sclerosis - pathology Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging Myelin neurite orientation dispersion and density imaging Neuroimaging neuroinflammation Neuromyelitis Neuromyelitis Optica - diagnostic imaging Neuromyelitis Optica - pathology neuronal loss Resonance Spatial analysis Spatial distribution Statistical analysis Substantia grisea synthetic magnetic resonance imaging White Matter - pathology
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