Testosterone Sustained Release Microspheres for the Treatment of Fecal Incontinence

The objective of this study was to develop a testosterone sustained release formulation for the treatment of fecal incontinence. To suppress the initial burst release of testosterone, which can lead to systemic toxicity, we incorporated a washing step using an aminoalkyl methacrylate copolymer E sol...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical sciences 2022-08, Vol.111 (8), p.2322-2329
Hauptverfasser:	Oe, Yusuke, Ogino, Shinichi, Kobayashi, Masanori, Kojima, Hiroyuki, Terukina, Takayuki, Kanazawa, Takanori, Kondo, Hiromu
Format:	Artikel
Sprache:	eng
Schlagworte:	Controlled release Long-acting Microsphere(s) Muscle(s) Polyglycolic acid (PLGA) Polylactic acid (PLA)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!