A multi-modal exploration of heterogeneous physico-chemical properties of DCIS breast microcalcifications

Ductal carcinoma in situ (DCIS) is frequently associated with breast calcification. This study combines multiple analytical techniques to investigate the heterogeneity of these calcifications at the micrometre scale. X-ray diffraction, scanning electron microscopy and Raman and Fourier-transform inf...

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Veröffentlicht in:	Analyst (London) 2022-04, Vol.147 (8), p.1641-1654
Hauptverfasser:	Gosling, Sarah, Calabrese, Doriana, Nallala, Jayakrupakar, Greenwood, Charlene, Pinder, Sarah, King, Lorraine, Marks, Jeffrey, Pinto, Donna, Lynch, Thomas, Lyburn, Iain D, Hwang, E. Shelley, Grand Challenge PRECISION Consortium, Rogers, Keith, Stone, Nicholas
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Breast Neoplasms Calcification Calcinosis - pathology Calcium phosphates Carcinoma, Intraductal, Noninfiltrating - pathology Chemical properties Chemistry Crystallography Durapatite Female Fourier transforms Heterogeneity Humans Hydroxyapatite Magnesium Paraffins Proteins Soft tissues Spectroscopy, Fourier Transform Infrared Tumor Microenvironment X-Ray Diffraction
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