Stereoretentive and regioselective selenium-catalyzed intermolecular propargylic C-H amination of alkynes

Herein we report an intermolecular propargylic C-H amination of alkynes. This reaction is operationally convenient and requires no transition metal catalysts or additives. Terminal, silyl, and internal alkynes bearing a wide range of functional groups can be aminated in high yields. The regioselecti...

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Veröffentlicht in:	Chemical science (Cambridge) 2022-02, Vol.13 (7), p.2121-2127
Hauptverfasser:	Maloney, T. Parker, Dohoda, Alexander F, Zhu, Alec C, Michael, Forrest E
Format:	Artikel
Sprache:	eng
Schlagworte:	Additives Alkynes Chemistry Destabilization Functional groups Isotopes Regioselectivity Selenium Substitution reactions Transition metals
Online-Zugang:	Volltext
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