Targeting toll-like receptors on T cells as a therapeutic strategy against tumors

•TLRs on T cells are involved in the regulation of T cell function.•TLRs serve as co-stimulatory molecules and activate T cell immunity.•Application of TLR agonists in activating T cell-mediated antitumor response.•Activation of both innate and adaptive immune response using TLR agonists is able to...

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