In unity, there is strength: Phase separation controls receptor tyrosine kinase signal transduction

Lin et al. (2022) discover that FGFR2 undergoes liquid-liquid phase separation with its downstream effectors SHP2 and PLCγ1, and the formation of phase separated condensates is essential for signaling competency. Lin et al. (2022) discover that FGFR2 undergoes liquid-liquid phase separation with its...

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Veröffentlicht in:	Molecular cell 2022-03, Vol.82 (6), p.1081-1083
Hauptverfasser:	Jimenez Salinas, Andres, Lee, Young Kwang
Format:	Artikel
Sprache:	eng
Schlagworte:	Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism Protein-Tyrosine Kinases - metabolism Signal Transduction
Online-Zugang:	Volltext
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