The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings
Objectives Examine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, ag...
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| Veröffentlicht in: | European journal of applied physiology 2022-06, Vol.122 (6), p.1441-1457 |
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| creator | Worts, P. R. Mason, J. R. Burkhart, S. O. Sanchez-Gonzalez, M. A. Kim, J-S. |
| description | Objectives
Examine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, age-stratified, non-concussed (HEALTHY) student-athletes.
Methods
Student-athletes between the ages of 13 and 18 that presented to the sports medicine clinic within Day 3–7 post-SRC and from local schools were recruited for a randomized controlled trial (RCT). The participants were administered the Vestibular/Ocular Motor Screening (VOMS), King-Devick (K-D), and Post-Concussion Symptom Scale (PCSS) before and after the intervention. Heart rate variability (HRV) and mean arterial pressure (MAP) were collected before, during, and after the intervention. The intervention was either a single, 20-min session of treadmill walking at 40% (40HR) or 60% of age-predicted max heart rate (60HR), or seated, rest (NOEX).
Results
30 participants completed the intervention with the SRC group treated 4.5 ± 1.3 days post-injury. Pre-exercise HRV and MAP were significantly different (
p
’s |
| doi_str_mv | 10.1007/s00421-022-04932-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2640994594</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2669222924</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-3fe5d0ff6af588f7987860cfc5e59e0425d335a3e9f85655eba76716316213d23</originalsourceid><addsrcrecordid>eNp9kUtv1TAQha0KRB_wB7pAltiwaMCP2Im7Q1VbkCqxKWvL1xm3rhLn4nFE77_H4ZYidcFqrPE3Z-boEHLK2SfOWPcZGWsFb5gQDWuNFE17QI54K02jpehePb-5OSTHiA-MsV7w_g05lEoyyTU7Ir9u74E6vxQ4o7jDAlP0FEIAX5DOgTrI82ZtPUL2EYHGRDN4SGXcUT8nvyDCQN0wj4Brm2JZhlobV-5HKIDndJthjFNMLu9oiGmI6Q7fktfBjQjvnuoJ-XF1eXvxtbn5fv3t4stN42WnSiMDqIGFoF1QfR8603e9Zj54BcpAta8GKZWTYEKvtFKwcZ3uePWsBZeDkCfk4153m-efC2CxU6x3jqNLMC9ohW6ZMa0ybUU_vEAf5iWnel2ltBFCGLFSYk_5PCNmCHab41StWc7sGovdx2JrLPZPLHYdev8kvWwmGJ5H_uZQAbkHsH6lO8j_dv9H9jcD-JkB</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2669222924</pqid></control><display><type>article</type><title>The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Worts, P. R. ; Mason, J. R. ; Burkhart, S. O. ; Sanchez-Gonzalez, M. A. ; Kim, J-S.</creator><creatorcontrib>Worts, P. R. ; Mason, J. R. ; Burkhart, S. O. ; Sanchez-Gonzalez, M. A. ; Kim, J-S.</creatorcontrib><description>Objectives
Examine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, age-stratified, non-concussed (HEALTHY) student-athletes.
Methods
Student-athletes between the ages of 13 and 18 that presented to the sports medicine clinic within Day 3–7 post-SRC and from local schools were recruited for a randomized controlled trial (RCT). The participants were administered the Vestibular/Ocular Motor Screening (VOMS), King-Devick (K-D), and Post-Concussion Symptom Scale (PCSS) before and after the intervention. Heart rate variability (HRV) and mean arterial pressure (MAP) were collected before, during, and after the intervention. The intervention was either a single, 20-min session of treadmill walking at 40% (40HR) or 60% of age-predicted max heart rate (60HR), or seated, rest (NOEX).
Results
30 participants completed the intervention with the SRC group treated 4.5 ± 1.3 days post-injury. Pre-exercise HRV and MAP were significantly different (
p
’s < 0.001) during treatment but returned to pre-exercise values within 5 min of recovery in both the SRC and HEALTHY groups. Both the SRC and HEALTHY groups exhibited similar reductions pre- to post-intervention for symptom severity and count (
p
’s < 0.05), three VOMS items (
p
’s < 0.05) but not K-D time.
Conclusions
To date, this is the first adolescent RCT to report the acute, systemic effects of aerobic exercise on recently concussed adolescent athletes. The interventions appeared safe in SRC participants, were well-tolerated, and provided brief therapeutic benefit.
Trial registration
Clinicaltrials.gov Identifier NCT03575455.</description><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/s00421-022-04932-4</identifier><identifier>PMID: 35303160</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acute effects ; Adolescent ; Aerobics ; Athletes ; Athletic Injuries - therapy ; Autonomic nervous system ; Biomedical and Life Sciences ; Biomedicine ; Blood pressure ; Brain Concussion - diagnosis ; Brain Concussion - therapy ; Concussion ; Exercise ; Heart rate ; Human Physiology ; Humans ; Intervention ; NCT ; NCT03575455 ; Occupational Medicine/Industrial Medicine ; Original Article ; Physical fitness ; Physical training ; Sports Medicine ; Student athletes ; Students ; Teenagers ; Vestibular system</subject><ispartof>European journal of applied physiology, 2022-06, Vol.122 (6), p.1441-1457</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-3fe5d0ff6af588f7987860cfc5e59e0425d335a3e9f85655eba76716316213d23</citedby><cites>FETCH-LOGICAL-c375t-3fe5d0ff6af588f7987860cfc5e59e0425d335a3e9f85655eba76716316213d23</cites><orcidid>0000-0002-5571-5404 ; 0000-0001-7452-8578 ; 0000-0002-7585-708X ; 0000-0003-0405-2281 ; 0000-0002-0992-8740</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00421-022-04932-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00421-022-04932-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35303160$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Worts, P. R.</creatorcontrib><creatorcontrib>Mason, J. R.</creatorcontrib><creatorcontrib>Burkhart, S. O.</creatorcontrib><creatorcontrib>Sanchez-Gonzalez, M. A.</creatorcontrib><creatorcontrib>Kim, J-S.</creatorcontrib><title>The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings</title><title>European journal of applied physiology</title><addtitle>Eur J Appl Physiol</addtitle><addtitle>Eur J Appl Physiol</addtitle><description>Objectives
Examine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, age-stratified, non-concussed (HEALTHY) student-athletes.
Methods
Student-athletes between the ages of 13 and 18 that presented to the sports medicine clinic within Day 3–7 post-SRC and from local schools were recruited for a randomized controlled trial (RCT). The participants were administered the Vestibular/Ocular Motor Screening (VOMS), King-Devick (K-D), and Post-Concussion Symptom Scale (PCSS) before and after the intervention. Heart rate variability (HRV) and mean arterial pressure (MAP) were collected before, during, and after the intervention. The intervention was either a single, 20-min session of treadmill walking at 40% (40HR) or 60% of age-predicted max heart rate (60HR), or seated, rest (NOEX).
Results
30 participants completed the intervention with the SRC group treated 4.5 ± 1.3 days post-injury. Pre-exercise HRV and MAP were significantly different (
p
’s < 0.001) during treatment but returned to pre-exercise values within 5 min of recovery in both the SRC and HEALTHY groups. Both the SRC and HEALTHY groups exhibited similar reductions pre- to post-intervention for symptom severity and count (
p
’s < 0.05), three VOMS items (
p
’s < 0.05) but not K-D time.
Conclusions
To date, this is the first adolescent RCT to report the acute, systemic effects of aerobic exercise on recently concussed adolescent athletes. The interventions appeared safe in SRC participants, were well-tolerated, and provided brief therapeutic benefit.
Trial registration
Clinicaltrials.gov Identifier NCT03575455.</description><subject>Acute effects</subject><subject>Adolescent</subject><subject>Aerobics</subject><subject>Athletes</subject><subject>Athletic Injuries - therapy</subject><subject>Autonomic nervous system</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blood pressure</subject><subject>Brain Concussion - diagnosis</subject><subject>Brain Concussion - therapy</subject><subject>Concussion</subject><subject>Exercise</subject><subject>Heart rate</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Intervention</subject><subject>NCT</subject><subject>NCT03575455</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Original Article</subject><subject>Physical fitness</subject><subject>Physical training</subject><subject>Sports Medicine</subject><subject>Student athletes</subject><subject>Students</subject><subject>Teenagers</subject><subject>Vestibular system</subject><issn>1439-6319</issn><issn>1439-6327</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUtv1TAQha0KRB_wB7pAltiwaMCP2Im7Q1VbkCqxKWvL1xm3rhLn4nFE77_H4ZYidcFqrPE3Z-boEHLK2SfOWPcZGWsFb5gQDWuNFE17QI54K02jpehePb-5OSTHiA-MsV7w_g05lEoyyTU7Ir9u74E6vxQ4o7jDAlP0FEIAX5DOgTrI82ZtPUL2EYHGRDN4SGXcUT8nvyDCQN0wj4Brm2JZhlobV-5HKIDndJthjFNMLu9oiGmI6Q7fktfBjQjvnuoJ-XF1eXvxtbn5fv3t4stN42WnSiMDqIGFoF1QfR8603e9Zj54BcpAta8GKZWTYEKvtFKwcZ3uePWsBZeDkCfk4153m-efC2CxU6x3jqNLMC9ohW6ZMa0ybUU_vEAf5iWnel2ltBFCGLFSYk_5PCNmCHab41StWc7sGovdx2JrLPZPLHYdev8kvWwmGJ5H_uZQAbkHsH6lO8j_dv9H9jcD-JkB</recordid><startdate>20220601</startdate><enddate>20220601</enddate><creator>Worts, P. R.</creator><creator>Mason, J. R.</creator><creator>Burkhart, S. O.</creator><creator>Sanchez-Gonzalez, M. A.</creator><creator>Kim, J-S.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5571-5404</orcidid><orcidid>https://orcid.org/0000-0001-7452-8578</orcidid><orcidid>https://orcid.org/0000-0002-7585-708X</orcidid><orcidid>https://orcid.org/0000-0003-0405-2281</orcidid><orcidid>https://orcid.org/0000-0002-0992-8740</orcidid></search><sort><creationdate>20220601</creationdate><title>The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings</title><author>Worts, P. R. ; Mason, J. R. ; Burkhart, S. O. ; Sanchez-Gonzalez, M. A. ; Kim, J-S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-3fe5d0ff6af588f7987860cfc5e59e0425d335a3e9f85655eba76716316213d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acute effects</topic><topic>Adolescent</topic><topic>Aerobics</topic><topic>Athletes</topic><topic>Athletic Injuries - therapy</topic><topic>Autonomic nervous system</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Blood pressure</topic><topic>Brain Concussion - diagnosis</topic><topic>Brain Concussion - therapy</topic><topic>Concussion</topic><topic>Exercise</topic><topic>Heart rate</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Intervention</topic><topic>NCT</topic><topic>NCT03575455</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Original Article</topic><topic>Physical fitness</topic><topic>Physical training</topic><topic>Sports Medicine</topic><topic>Student athletes</topic><topic>Students</topic><topic>Teenagers</topic><topic>Vestibular system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Worts, P. R.</creatorcontrib><creatorcontrib>Mason, J. R.</creatorcontrib><creatorcontrib>Burkhart, S. O.</creatorcontrib><creatorcontrib>Sanchez-Gonzalez, M. A.</creatorcontrib><creatorcontrib>Kim, J-S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of applied physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Worts, P. R.</au><au>Mason, J. R.</au><au>Burkhart, S. O.</au><au>Sanchez-Gonzalez, M. A.</au><au>Kim, J-S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings</atitle><jtitle>European journal of applied physiology</jtitle><stitle>Eur J Appl Physiol</stitle><addtitle>Eur J Appl Physiol</addtitle><date>2022-06-01</date><risdate>2022</risdate><volume>122</volume><issue>6</issue><spage>1441</spage><epage>1457</epage><pages>1441-1457</pages><issn>1439-6319</issn><eissn>1439-6327</eissn><abstract>Objectives
Examine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, age-stratified, non-concussed (HEALTHY) student-athletes.
Methods
Student-athletes between the ages of 13 and 18 that presented to the sports medicine clinic within Day 3–7 post-SRC and from local schools were recruited for a randomized controlled trial (RCT). The participants were administered the Vestibular/Ocular Motor Screening (VOMS), King-Devick (K-D), and Post-Concussion Symptom Scale (PCSS) before and after the intervention. Heart rate variability (HRV) and mean arterial pressure (MAP) were collected before, during, and after the intervention. The intervention was either a single, 20-min session of treadmill walking at 40% (40HR) or 60% of age-predicted max heart rate (60HR), or seated, rest (NOEX).
Results
30 participants completed the intervention with the SRC group treated 4.5 ± 1.3 days post-injury. Pre-exercise HRV and MAP were significantly different (
p
’s < 0.001) during treatment but returned to pre-exercise values within 5 min of recovery in both the SRC and HEALTHY groups. Both the SRC and HEALTHY groups exhibited similar reductions pre- to post-intervention for symptom severity and count (
p
’s < 0.05), three VOMS items (
p
’s < 0.05) but not K-D time.
Conclusions
To date, this is the first adolescent RCT to report the acute, systemic effects of aerobic exercise on recently concussed adolescent athletes. The interventions appeared safe in SRC participants, were well-tolerated, and provided brief therapeutic benefit.
Trial registration
Clinicaltrials.gov Identifier NCT03575455.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>35303160</pmid><doi>10.1007/s00421-022-04932-4</doi><tpages>17</tpages><orcidid>https://orcid.org/0000-0002-5571-5404</orcidid><orcidid>https://orcid.org/0000-0001-7452-8578</orcidid><orcidid>https://orcid.org/0000-0002-7585-708X</orcidid><orcidid>https://orcid.org/0000-0003-0405-2281</orcidid><orcidid>https://orcid.org/0000-0002-0992-8740</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1439-6319 |
| ispartof | European journal of applied physiology, 2022-06, Vol.122 (6), p.1441-1457 |
| issn | 1439-6319 1439-6327 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Acute effects Adolescent Aerobics Athletes Athletic Injuries - therapy Autonomic nervous system Biomedical and Life Sciences Biomedicine Blood pressure Brain Concussion - diagnosis Brain Concussion - therapy Concussion Exercise Heart rate Human Physiology Humans Intervention NCT NCT03575455 Occupational Medicine/Industrial Medicine Original Article Physical fitness Physical training Sports Medicine Student athletes Students Teenagers Vestibular system |
| title | The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings |
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