Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway

The aryl hydrocarbon receptor (AhR) mediates various cellular responses upon exposure to exogenous and endogenous stress factors. In these responses, AhR plays a dual role as a stress sensor for detecting various AhR ligands and as a transcription factor that upregulates the expression of downstream...

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Veröffentlicht in:	Toxicology (Amsterdam) 2022-03, Vol.470, p.153154-153154, Article 153154
Hauptverfasser:	Habano, Wataru, Miura, Toshitaka, Terashima, Jun, Ozawa, Shogo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aryl hydrocarbon receptor aryl hydrocarbon receptors chronic exposure DNA Methylation DNA methylation modulator DNA methylation reader Gene Expression Regulation homeostasis kynurenine Ligands Receptors, Aryl Hydrocarbon - genetics Receptors, Aryl Hydrocarbon - metabolism Stress response toxicology Xenobiotic responsive element xenobiotics Xenobiotics - metabolism
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