Toxification metabolism and treatment strategy of the chiral triazole fungicide prothioconazole in water

Toxification metabolism of the chiral triazole fungicide prothioconazole in the environment has attracted an increasing amount of attention. To better understand the fate of prothioconazole in aquatic ecosystems and develop a treatment strategy, the stereoselective toxicity, degradation and bioconce...

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Veröffentlicht in:Journal of hazardous materials 2022-06, Vol.432, p.128650-128650, Article 128650
Hauptverfasser: Zhang, Zhaoxian, Xie, Yiwen, Ye, Yingzi, Yang, Yaling, Hua, Rimao, Wu, Xiangwei
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Sprache:eng
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Zusammenfassung:Toxification metabolism of the chiral triazole fungicide prothioconazole in the environment has attracted an increasing amount of attention. To better understand the fate of prothioconazole in aquatic ecosystems and develop a treatment strategy, the stereoselective toxicity, degradation and bioconcentration of prothioconazole were investigated in water with algae at the enantiomer level. There was remarkable enantioselectivity against Chlorella pyrenoidosa, and the highly toxic S-prothioconazole was preferentially degraded with enantiomer fraction values ranging from 0.5 to 0.74. Metabolism experiment results showed that the parent compound was quickly eliminated driven by biodegradation and abiotic degradation (hydrolysis, photolysis). Fourteen phase I and two phase II metabolites involved in the reactions of hydroxylation, methylation, dechlorinating, desulfuration, dehydration and conjugation were identified, where prothioconazole-desthio was the major metabolite. The highly toxic metabolite prothioconazole-desthio persisted in water and hardly degraded with or without C. pyrenoidosa. Furthermore, the reaction system including 1 mg of cobalt coated in nitrogen doped carbon nanotubes and 0.156 g of peroxymonosulfate was used to eliminate prothioconazole-desthio. Approximately 96% prothioconazole-desthio was eliminated and transformed to low toxicity metabolites. This work provides a strategy for the risk evaluation of prothioconazole in aquatic ecosystems and proposes a workable plan for the elimination of pesticide residues in water. [Display omitted] •Prothioconazole could be transformed to high toxic metabolite in water.•Potential metabolic pathway of prothioconazole including phase I and II was proposed.•Highly toxicity metabolite prothioconazole-desthio could persist in water.•The prothioconazole-desthio was removed by catalytic oxidation method.
ISSN:0304-3894
1873-3336
DOI:10.1016/j.jhazmat.2022.128650