Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1

Abstract O-GlcNAc modification of Notch receptors regulates Notch ligand interactions in a manner distinct from other forms of O-glycans on epidermal growth factor (EGF)-like repeats of Notch receptors. Although many proteins, besides Notch receptors, are expected to be O-GlcNAcylated by EGF domain-...

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Veröffentlicht in:	Glycobiology (Oxford) 2022-06, Vol.32 (7), p.616-628
Hauptverfasser:	Tsukamoto, Yohei, Ogawa, Mitsutaka, Yogi, Kentarou, Tashima, Yuko, Takeuchi, Hideyuki, Okajima, Tetsuya
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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