Small extracellular vesicles from iPSC-derived mesenchymal stem cells ameliorate tendinopathy pain by inhibiting mast cell activation

This study aimed to explore the effect of small extracellular vesicles from induced pluripotent stem cell-derived mesenchymal stem cells (iMSC-sEVs) on acute pain and investigate the underlying mechanisms. The pathology of tendons was accessed by hematoxylin and eosin staining, immunohistochemical a...

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Veröffentlicht in:	Nanomedicine (London, England) England), 2022-04, Vol.17 (8), p.513-529
Hauptverfasser:	Gao, Renzhi, Ye, Teng, Zhu, Zhaochen, Li, Qing, Zhang, Juntao, Yuan, Ji, Zhao, Bizeng, Xie, Zongping, Wang, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Pain - metabolism Extracellular Vesicles - metabolism Humans iMSC-sEV Induced Pluripotent Stem Cells mast cell Mast Cells Mesenchymal Stem Cells - metabolism pain tendinopathy Tendinopathy - metabolism Tendinopathy - therapy
Online-Zugang:	Volltext
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