Ameliorative role of naringenin against lead‐induced genetic damage and oxidative stress in cultured human lymphocytes

Lead (Pb) is a ubiquitous toxic heavy metal that is known to induce damage to major macromolecules (lipids, proteins, and nucleic acids) by enhancing the level of reactive oxygen species (ROS). Naringenin, a predominant flavonoid primarily found in citrus fruits has attained increasing attention due...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2022-06, Vol.36 (6), p.e23036-n/a
Hauptverfasser:	Yadav, Bharti, Vishwakarma, Veena, Kumar, Sunil, Aggarwal, Neeraj K., Gupta, Ranjan, Yadav, Anita
Format:	Artikel
Sprache:	eng
Schlagworte:	antioxidant Antioxidants - metabolism Antioxidants - pharmacology Bioassays Catalase Catalase - metabolism Chromosome aberrations Citrus fruits Comet assay Damage Flavanones Flavonoids Genotoxicity Glutathione Glutathione - metabolism Glutathione peroxidase Glutathione Peroxidase - metabolism Heavy metals Humans Lead Lead - toxicity Lipid Peroxidation Lipids Lymphocytes Lymphocytes - metabolism Macromolecules Naringenin Nucleic acids Oxidative Stress Peripheral blood Peroxidase Peroxidation Reactive oxygen species Sister chromatid exchange Superoxide dismutase Superoxide Dismutase - metabolism Toxicity
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